Our Research

Our Research

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Contact Details

  Street address:
Level 11, KGV Building
Missenden Road
Postal address:
Post Office Box M30
Missenden Road NSW 2050

Phone: (02) 9515-6111
Fax: (02) 9515-9610

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Clinical Immunology

Our Research

Professor Britton's research focuses on the immunology of tuberculosis and the development of more effective vaccines and drugs against this major human infectious disease that causes about 9 million cases and 1.5 million deaths each year. He is is CIA on the NHMRC CRE in Tuberculosis Control undertaking research into improved methods of controlling TB through contact investigation in high burden countries. They have also identified the association of genetic variants with increased risk of tuberculosis in Vietnamese.

Research Staff

  • A/Professor Stephen Adelstein, Head of Department, Immunology RPAH
  • Professor Warwick Britton
  • Dr Roger Garsia
  • Dr Louise Weinholt

Publications and Presentations

Publication Details:
  1. Fox, G., Loan, L., Viet Nhung, N., Loi, N., Sy, D., Britton, W., Marks, G. (2015). Barriers to adherence with tuberculosis contact investigation in six provinces of Vietnam: a nested case-control study. BMC Infectious Diseases, 15(1), 1-8.
  2. Florido, M., Pillay, R., Gillis, C., Xia, Y., Turner, S., Triccas, J., Stambas, J., Britton, W. (2015). Epitope-specific CD4(+) , but not CD8(+) , T-cell responses induced by recombinant influenza A viruses protect against Mycobacterium tuberculosis infection. European Journal of Immunology, 45(3), 780-793.
  3. Barry, S., Chan, B., Ellis, M., Yang, Y., Plit, M., Guan, G., Wang, X., Britton, W., Saunders, B. (2015). Identification of miR-93 as a suitable miR for normalizing miRNA in plasma of tuberculosis patients. Journal of Cellular and Molecular Medicine, 19(7), 1606-1613.
  4. Hare, N., Chan, B., Chan, E., Kaufman (nee Alexander), K., Britton, W., Saunders, B. (2015). Microparticles released from Mycobacterium tuberculosis-infected human macrophages contain increased levels of the type I interferon inducible proteins including ISG15. Proteomics, 15(17), 3020-3029.
  5. Chan, J., Tyne, A., Pang, A., McLachlan, A., Perera, V., Chan, J., Britton, W., Chan, K., Duke, C., Young, P., Traini, D. (2015). Murine pharmacokinetics of rifapentine delivered as an inhalable dry powder. International Journal of Antimicrobial Agents, 45(3), 319-323.
  6. Hardy, T., O’Brien, B., Gerbis, N., Barnett, M., Reddel, S., Brewer, J., Herkes, G., Silberstein, P., Garsia, R., Watson, J., Gupta, R., Parratt, J., et al (2015). Brain histopathology in three cases of Susac's syndrome: Implications for lesion pathogenesis and treatment. Journal of Neurology, Neurosurgery, and Psychiatry, 86(5), 582-584.
  7. Nguyen, M., Garsia, R. (2015). Burning vessels: A review of vasculitis for primary care. Medicine Today, 16(3), 26-39.
  8. Wightman, F., Solomon, A., Kumar, S., Urriola, N., Gallagher, K., Hiener, B., Palmer, S., Garsia, R., McNeil, C., Lewin, S. (2015). Effect of ipilimumab on the HIV reservoir in an HIV-infected individual with metastatic melanoma. AIDS, 29(4), 504-506.
  9. Ma, C., Wong, N., Rao, G., Avery, D., Torpy, J., Hambridge, T., Bustamante, J., Okada, S., Stoddard, J., Deenick, E., Campbell, D., Adelstein, S., Fulcher, D., et al (2015). Monogenic mutations differentially affect the quantity and quality of T follicular helper cells in patients with human primary immunodeficiencies. Journal of Allergy and Clinical Immunology, 136(4), 993-1006.
  10. Wilson, R., Ives, M., Rao, G., Lau, A., Payne, K., Kobayashi, M., Arkwright, P., Peake, J., Wong, M., Adelstein, S., et al (2015). STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function. The Journal of Experimental Medicine, 212(6), 865-864.

Contact details for department

Head of Department: A/Professor Stephen Adelstein

Department/Unit: Clinical Immunology
RPA Hospital
Missenden Road
Camperdown NSW 2050
Telephone: (02) 9515 6111
Facsimile: (02) 9515 9610
Web: http://www.slhd.nsw.gov.au/research/
Email: warwick.britton@sswahs.nsw.gov.au