Our Research

Our Research

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Contact Details

  Street address:
Level 11, KGV Building
Missenden Road
Postal address:
Post Office Box M30
Missenden Road NSW 2050

Phone: (02) 9515-6111
Fax: (02) 9515-9610

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Renal Medicine

Our Research

The Department of Renal Medicine and Transplantation has a range of ongoing research projects spanning from basic science (immunology of kidney transplant rejection and kidney disease), through clinical trials (immunosuppression in kidney transplantation, diabetes after transplantation, new therapies in kidney disease), policy and practice (cost of chronic kidney disease, patient relevant outcomes, burden of diabetic nephropathy, access to kidney transplantation) to health outcomes (long-term outcomes after kidney transplantation, cancer after transplantation, disease recurrence). Our goals are to pursue new advances in understanding, preventing and managing kidney disease with the aim of easing the burden that kidney disease imparts upon our patients and our society.

Publications and Presentations

Publication Details:
  1. Wong G, Chua S, Chadban SJ, Clayton P, Pilmore H, Hughes PD, Ferrari P, Lim WH. Waiting Time Between Failure of First Graft and Second Kidney Transplant and Graft and Patient Survival. Transplantation. 2015 Oct 9. [Epub ahead of print] PubMed PMID: 26457605.
  2. Howard K, Jan S, Rose JM, Wong G, Craig JC, Irving M, Tong A, Chadban S, Allen, RD, Cass A. Preferences for Policy Options for Deceased Organ Donation for Transplantation: A Discrete Choice Experiment. Transplantation. 2015 Oct 9. [Epub ahead of print] PubMed PMID: 26457603.
  3. Hanson CS, Chadban SJ, Chapman JR, Craig JC, Wong G, Tong A. Nephrologists' Perspectives on Recipient Eligibility and Access to Living Kidney Donor Transplantation. Transplantation. 2015 Oct 1.
  4. Matsushita K, Coresh J, Sang Y, Chalmers J, Fox C, Guallar E, Jafar T, Jassal SK, Landman GW, Muntner P, Roderick P, Sairenchi T, Schöttker B, Shankar A, Shlipak M, Tonelli M, Townend J, van Zuilen A, Yamagishi K, Yamashita K, Gansevoort R, Sarnak M, Warnock DG, Woodward M, Ärnlöv J; CKD Prognosis Consortium. Estimated glomerular filtration rate and albuminuria for prediction of cardiovascular outcomes: a collaborative meta-analysis of individual participant data. Lancet Diabetes Endocrinol. 2015 Jul;3(7):514-25.
  5. Zykova SN, Storhaug HM, Toft I, Chadban SJ, Jenssen TG, White SL. Cross-sectional analysis of nutrition and serum uric acid in two Caucasian cohorts: the AusDiab Study and the Tromsø study. Nutr J. 2015 May 14;14:49.
  6. Wyld ML, Lee CM, Zhuo X, White S, Shaw JE, Morton RL, Colagiuri S, Chadban SJ. Cost to government and society of chronic kidney disease stage 1-5: a national cohort study. Intern Med J. 2015 Jul;45(7):741-7.
  7. Tong A, Crowe S, Chando S, Cass A, Chadban SJ, Chapman JR, Gallagher M, Hawley CM, Hill S, Howard K, Johnson DW, Kerr PG, McKenzie A, Parker D, Perkovic V, Polkinghorne KR, Pollock C, Strippoli GF, Tugwell P, Walker RG, Webster AC, Wong G, Craig JC. Research Priorities in CKD: Report of a National Workshop Conducted in Australia. Am J Kidney Dis. 2015 Aug;66(2):212-22.
  8. Clayton PA, Aouad L, Wyburn KR, Eris JM, Chadban SJ. HbA1c Is Insensitive at Month 3 After Kidney Transplantation. Transplantation. 2015 May;99(5):e37-8.
  9. Wang AY, Bellomo R, Cass A, Finfer S, Gattas D, Myburgh J, Chadban S, Hirakawa Y, Ninomiya T, Li Q, Lo S, Barzi F, Sukkar L, Jardine M, Gallagher MP; POST-RENAL Study Investigators and the ANZICS Clinical Trials Group. Health-related quality of life in survivors of acute kidney injury: The Prolonged Outcomes Study of the Randomized Evaluation of Normal versus?Augmented Level Replacement Therapy study outcomes. Nephrology (Carlton). 2015 Jul;20(7):492-8.
  10. Kwan T, Chadban SJ, Ma J, Bao S, Alexander SI, Wu H. IL-17 deficiency attenuates allograft injury and prolongs survival in a murine model of fully MHC-mismatched renal allograft transplantation. Am J Transplant. 2015 Jun;15(6):1555-67.
  11. Aggarwal S, Sukkar L, Wynter L, Richards K, Cheung J, Chadban SJ. Dangers of broth after transplantation. Nephrology (Carlton). 2015 Apr;20(4):297-9.
  12. Howard K, Jan S, Rose JM, Wong G, Irving M, Tong A, Craig JC, Chadban S, Allen RD, Cass A. Community preferences for the allocation of donor organs for transplantation: a discrete choice study. Transplantation. 2015 Mar;99(3):560-7.
  13. Lim WH, Gray NA, Chadban SJ, Pilmore H, Wong G. Graft and patient outcomes of zero-human leucocyte-antigen-mismatched deceased and live donor kidney transplant recipients. Transpl Int. 2015 May;28(5):610-8.
  14. Wyld ML, Clayton PA, Kennedy SE, Alexander SI, Chadban SJ. Pregnancy outcomes for kidney transplant recipients with transplantation as a child. JAMA Pediatr. 2015 Feb;169(2):e143626.
  15. Hanson CS, Chadban SJ, Chapman JR, Craig JC, Wong G, Ralph AF, Tong A. The expectations and attitudes of patients with chronic kidney disease toward living kidney donor transplantation: a thematic synthesis of qualitative studies. Transplantation. 2015 Mar;99(3):540-54.
  16. Zhang L, Badve SV, Pascoe EM, Beller E, Cass A, Clark C, de Zoysa J, Isbel NM, McTaggart S, Morrish AT, Playford EG, Scaria A, Snelling P, Vergara LA, Hawley CM, Johnson DW; HONEYPOT Study Collaborative Group. The Effect of Exit-Site Antibacterial Honey Versus Nasal Mupirocin Prophylaxis on the Microbiology and Outcomes of Peritoneal Dialysis-Associated Peritonitis and Exit-Site Infections: A Sub-Study of the Honeypot Trial. Perit Dial Int. 2015 Dec;35(7):712-21.
  17. Lan PG, Clayton PA, Saunders J, Polkinghorne KR, Snelling PL. Predictors and outcomes of transfers from peritoneal dialysis to hemodialysis. Perit Dial Int. 2015 May-Jun;35(3):306-15.
  18. Foote C, Clayton PA, Johnson DW, Jardine M, Snelling P, Cass A. Impact of estimated GFR reporting on late referral rates and practice patterns for end-stage kidney disease patients: a multilevel logistic regression analysis using the Australia and New Zealand Dialysis and Transplant Registry (ANZDATA). Am J Kidney Dis. 2014 Sep;64(3):359-66.
  19. Muir CA, Kotwal SS, Hawley CM, Polkinghorne K, Gallagher MP, Snelling P, Jardine MJ. Buttonhole cannulation and clinical outcomes in a home hemodialysis cohort and systematic review. Clin J Am Soc Nephrol. 2014 Jan;9(1):110-9.
  20. Johnson DW, Badve SV, Pascoe EM, Beller E, Cass A, Clark C, de Zoysa J, Isbel NM, McTaggart S, Morrish AT, Playford EG, Scaria A, Snelling P, Vergara LA, Hawley CM; HONEYPOT Study Collaborative Group. Antibacterial honey for the prevention of peritoneal-dialysis-related infections (HONEYPOT): a randomized trial. Lancet Infect Dis. 2014 Jan;14(1):23-30.
  21. Tong A, Manns B, Hemmelgarn B, Wheeler DC, Tugwell P, Winkelmayer WC, van Biesen W, Crowe S, Kerr PG, Polkinghorne KR, Howard K, Pollock C, Hawley CM, Johnson DW, McDonald SP, Gallagher MP, Urquhart-Secord R, Craig JC; SONG-HD Collaboration. Standardised outcomes in nephrology - Haemodialysis (SONG-HD): study protocol for establishing a core outcome set in haemodialysis. Trials. 2015 Aug 19;16:364.
  22. Kotwal S, Webster A, Cass A, Gallagher M. Rural Versus Urban Health Service Utilization and Outcomes for Renal Patients in New South Wales: Protocol for a Data Linkage Study. JMIR Res Protoc. 2015 Jun 16;4(2):e73.
  23. Kang A, Nigwekar SU, Perkovic V, Kulshrestha S, Zoungas S, Navaneethan SD, Cass A, Gallagher MP, Ninomiya T, Strippoli GF, Jardine MJ. Interventions for lowering plasma homocysteine levels in kidney transplant recipients. Cochrane Database Syst Rev. 2015 May 4;(5):CD007910.
  24. Liyanage T, Ninomiya T, Jha V, Neal B, Patrice HM, Okpechi I, Zhao MH, Lv J, Garg AX, Knight J, Rodgers A, Gallagher M, Kotwal S, Cass A, Perkovic V. Worldwide access to treatment for end-stage kidney disease: a systematic review. Lancet. 2015 May 16;385(9981):1975-82.
  25. Jha V, John O, Joshi R, Kotwal S, Essue B, Jan S, Gallagher M, Knight J. Dialysis outcomes in India: a pilot study. Nephrology (Carlton). 2015 May;20(5):329-34.
  26. Jardine MJ, Zuo LI, Gray NA, de Zoysa J, Chan CT, Gallagher MP, Howard K, Hertier S, Cass A, Perkovic V; ACTIVE Dialysis Steering Committee. Design and participant baseline characteristics of 'A Clinical Trial of IntensiVE Dialysis': the ACTIVE Dialysis Study. Nephrology (Carlton). 2015 Apr;20(4):257-65.
  27. Campbell DJ, Johnson DW, Mudge DW, Gallagher MP, Craig JC. Prevention of peritoneal dialysis-related infections. Nephrol Dial Transplant. 2015 Sep;30(9):1461-72.
  28. Haller MC, van der Veer SN, Nagler EV, Tomson C, Lewington A, Hemmelgarn BR, Gallagher M, Rocco M, Obrador G, Vanholder R, Craig JC, van Biesen W. A survey on the methodological processes and policies of renal guideline groups as a first step to harmonize renal guidelines. Nephrol Dial Transplant. 2015 Jul;30(7):1066-74.
  29. Bellomo R, Cass A, Cole L, Finfer S, Gallagher M, Lee J, Lo S, McArthur C, McGuinness S, Norton R, Myburgh J, Sheinkestel C; RENAL Study Investigators. Daily protein intake and patient outcomes in severe acute kidney injury: findings of the randomized evaluation of normal versus augmented level of replacement therapy (RENAL) trial. Blood Purif. 2014;37(4):325-34.
  30. Foote C, Morton RL, Jardine M, Gallagher M, Brown M, Howard K, Cass A. COnsiderations of Nephrologists when SuggestIng Dialysis in Elderly patients with Renal failure (CONSIDER): a discrete choice experiment. Nephrol Dial Transplant. 2014 Dec;29(12):2302-9.

Contact details for department

Head of Department: Professor Steve Chadban

Department/Unit: Renal Medicine
RPA Hospital
Missenden Road
Camperdown NSW 2050
Telephone: 9515 6600
Facsimile: 9515 6329
Web: http://www.slhd.nsw.gov.au/research/
Email: steve.chadban@sswahs.nsw.gov.au