Our Research

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Contact Details

  Street address:
Level 11, KGV Building
Missenden Road
CAMPERDOWN NSW 2050
 
Postal address:
Post Office Box M30
Missenden Road NSW 2050

Phone: (02) 9515-6111
Fax: (02) 9515-9610

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Thoracic Medicine

Thoracic Medicine

Our Research

Department Overview

The Department of Thoracic Medicine pursues a diverse range of research from basic clinical and applied physiology to innovation in clinical care. The Department is one of Australia-s most active clinical laboratories with a focus on translational research while maintaining a strong focus on undergraduate and postgraduate education. In 2015 there were nine enrolled PhD candidates undertaking work wholly or partly within the Department. Senior members of the Department have maintained a strong commitment with local and international professional societies and are regarded as experts in their field.

Investigator-initiated Studies

Our Department-s research activities focus on five main streams; Airways physiology, cilia function, effects of hypoxia on cardio-respiratory function, sleep medicine, and interventional pulmonology. The laboratory is conducting a number of studies evaluating novel measures of airway function with a focus on translational research into small airway structure and function. These studies are conducted in collaboration with the Woolcock Institute of Medical research and Sydney University. Other research collaborations in 2015 included the Concord Hospital Departments of Cardiology, Endocrinology and Nuclear Medicine, Macquarie University, University of Tasmania, Adelaide University, University of Technology and Royal North Shore Hospital.

Clinical Trials

The Department continues to be active in a range of Clinical Trials, some funded by Industry and others via NH&MRC, that study the effects of new and novel therapeutical interventions for the treatment of asthma, interstitial lung disease, bronchiectasis and chronic obstructive pulmonary disease (COPD).

Clinical Care Initiatives

In keeping with a focus on improving patient care and clinically relevant research, the Department has developed sub-specialty clinics for airways Diseases (including asthma and COPD), bronchiectasis, primary ciliary dyskinesia, sleep medicine and a metabolic-respiratory failure clinic. Regular multidisciplinary meetings are also conducted for interstitial lung disease and lung cancer. Our Department-s research activities focus on five main streams; Airways physiology, cilia function, effects of hypoxia on cardio-respiratory function, sleep medicine, and interventional pulmonology. The laboratory is conducting a number of studies evaluating novel measures of airway function with a focus on translational research into small airway structure and function. These studies are conducted in collaboration with the Woolcock Institute of Medical research and Sydney University. Other research collaborations in 2015 included the Concord Hospital Departments of Cardiology, Endocrinology and Nuclear Medicine, Macquarie University, University of Tasmania, Adelaide University, University of Technology and Royal North Shore Hospital.

Key Achievements

  • Clinical Professor Peters: Past-President of the Thoracic Society of Australia and New Zealand.
  • Clinical Associate Professor Rutland: President of NSW Branch of the TSANZ.
  • Dr Claude Farah: Convenor of Special Interest Group - Physiology and Sleep Medicine TSANZ and co-convenor 'Flow Volume Underworld'.
  • Dr Leigh Seccombe: Member of the Science and Conference Committee ANZSRS and was awarded her PhD from Macquarie University.
  • Clinical Professor Christine Jenkins: Steering committee of the Global Initiative for Chronic Lung Disease & Chair Australian Lung Foundation.

Research Staff

Investigator/Sub Investigator:

  • Professor Matthew Peters
  • Professor Christine Jenkins
  • Professor Alvin Ing
  • Professor Jonathon Rutland
  • Dr Leon Laks
  • Dr Ruby Brillante
  • Professor Lucy Morgan
  • Dr Elizabeth Veitch
  • Dr Claude Farah
  • Dr Tajalli Saghaie

Scientist:

  • Dr Leigh Seccombe
  • Ms Gavina Cossa
  • Mr Lachlan Buddle
  • Mr Peter Rogers

Research Nurses:

  • Mrs Kerrie Wade
  • Ms Tessa Bird

Higher Degree Students:

PhD:

  • Dr Kelvin Hsu
  • Ms Kathy Barnsley
  • Ms Kristin Carson
  • Dr Stephen Milne
  • Dr Katrina Tonga
  • Ms Kanika Jetmalani
  • Dr Sabine Zimmerman
  • Ms Alesha Mitchell


Publications and Presentations

Publication Details:
  1. Gao P, Gibson PG, Baines KJ, Yang IA, Upham JW, Reynolds PN, Hodge S, James AL, Jenkins C, Peters MJ, Zhang J, Simpson JL. Anti-inflammatory deficiencies in neutrophilic asthma: reduced galectin-3 and IL-1RA/IL-1ß Respir Res. 2015;16:5.
  2. Farah CS, Keulers LA, Hardaker KM, Peters MJ, Berend N, Postma DS, Salome CM, King GG. Association between peripheral airway function and neutrophilic inflammation in asthma. Respirology. 2015 ;20 : 975-81.
  3. Daube M, Eastwood P, Mishima M, Peters M. Tobacco plain packaging: the Australian experience. Respirology. 2015;20:1001-3.
  4. Reddel HK, Sawyer S, Everett P, Flood P, Peters MJ. Asthma control in Australia: results of a cross-sectional web-based survey in a large nationally representative population. Med J Aust 2015; 202(9):492-7.
  5. Hosie, P.H., Fitzgerald, D.A., Jaffe, A., Birman, C.S., Rutland, J., Morgan, L.C. 2015. Presentation of primary ciliary dyskinesia in children: 30 years' experience. J Paediatr Child Health 51(7), 722-6.
  6. Anzueto, A., Jenkins, C.R., Make, B.J., Lindberg, M., Calverley, P.M., Fageras, M., Postma, D.S., Rennard, S.I., Tashkin, D.P. 2015. Efficacy of an inhaled corticosteroid/long-acting beta2-agonist combination in symptomatic COPD patients in GOLD groups B and D. Eur Respir J 46(1), 255-8
  7. Make, B.J., Eriksson, G., Calverley, P.M., Jenkins, C.R., Postma, D.S., Peterson, S., Ostlund, O., Anzueto, A. 2015. A score to predict short-term risk of COPD exacerbations (SCOPEX). Int J Chron Obstruct Pulmon Dis 10, 201-9.
  8. Smith, T.A., Davidson, P.M., Jenkins, C.R., Ingham, J.M. 2015. Life behind the mask: the patient experience of NIV. The Lancet Respiratory medicine 3(1), 8-10.
  9. Jetmalani, K., Timmins, S., Brown, N.J., Diba, C., Berend, N., Salome, C.M., Wen, F.Q., Chen, P., King, G.G., Farah, C.S. 2015. Expiratory flow limitation relates to symptoms during COPD exacerbations requiring hospital admission. Int J Chron Obstruct Pulmon Dis 10, 939-45.
  10. Leung RWM, McKeough ZJ, Peters MJ, Alison JA. Experiences and perceptions of the short-form Sun-style Tai Chi training in Caucasians with COPD. European Journal of Integrative Medicine. 2015;7(2):131-5.
  11. Leung RW, McKeough ZJ, Alison JA. Tai Chi as a form of exercise training in people with chronic obstructive pulmonary disease. Expert Rev Respir Med. 2013 2013-Dec;7(6):587-92. PubMed PMID: MEDLINE:24224506.
  12. Tulbah, A.S., Ong, H.X., Morgan, L., Colombo, P., Young, P.M., Traini, D. 2015. Dry powder formulation of simvastatin. Expert opinion on drug delivery 12(6), 857-68. doi:10.1517/17425247.2015.963054.
  13. Chung Y, Morgan L. Pneumonia: who is at risk in your practice? Med Today 2015; 16(8): 35-42.
  14. Morgan, LC, Birman, CS The impact of Primary Ciliary Dyskinesia on the upper respiratory tract. Paediatric Respiratory Reviews 2015 Oct 23. pii: S1526-0542(15)00091-3.
  15. Chan KC, Ing AJ, Birring SS: 'Chronic Cough and Obstructive Sleep Apnoea' Pulmonary Pharmacology and Therapeutics 2015: (35) 129-131.
  16. Naoum C, Kritharides L, Ing AJ, Falk G and Yiannikas JY. 'Changes in lung volumes and gas-trapping in patients with large hiatal hernia' Clin Respir J 2015: DOI: 10.1111/crj.12314
  17. Falk GL, Beattie J, Ing AJ, Falk SE, Magee M, Burton L, Van der Wall H. Scintigraphy in laryngopharyngeal and gastroesophageal reflux disease: A definitive diagnostic test? World J of Gastroenterol: 03/2015; 21(12):3619-27.
  18. Beasley R, Chien J, Douglas J, Eastlake L, Farah CS, King GG, Moore R, Pilcher J, Richards M, Smith S, Walter H. Thoracic Society of Australia and New Zealand oxygen guidelines for acute oxygen use in adults: 'Swimming between the flags'. Respirology 2015; 20:1182-1191.

Contact details for department

Head of Department: Professor Matthew Peters

Department/Unit: Thoracic Medicine
Address:
Concord Hospital
Hospital Road
Concord NSW 2139
Telephone: (02) 9767 6712
Facsimile: (02) 9767 6991
Web: www.slhd.nsw.gov.au/research/default.html
Email: Matthew.Peters@sswahs.nsw.gov.au