Royal Prince Alfred Hospital Royal Prince Alfred Hospital
Department of Neuropathology


The RPA Department of Neuropathology is the only Neuropathology Department in NSW. It provides subspecialist diagnostic expertise on a wide variety of neurosurgical and forensic neurological specimens. Its main functions are: 

  • Providing tissue-based diagnostic services for the RPA Neurosurgery and Neurology Departments.
  • Providing a “second opinion” service for pathologists across the state and internationally.
  • Providing molecular testing services for brain tumours.
  • Acting as the NSW state referral laboratory for CJD diagnosis.
  • Providing subspecialist forensic neuropathology services to all three NSW forensic hubs.

The Neuropathology laboratory was established in 1986 in the Blackburn building of the University of Sydney. In 2013 it relocated to state of the art laboratories at the Brain and Mind Research Institute, University of Sydney. The Department provides training opportunities for anatomical pathology trainees as well as research students, and is closely affiliated with the University of Sydney Discipline of Pathology and Central Clinical School. It also actively contributes to medical student teaching at the University of Sydney.