Our Research

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Contact Details

  Street address:
Level 11, KGV Building
Missenden Road
CAMPERDOWN NSW 2050
 
Postal address:
Post Office Box M30
Missenden Road NSW 2050

Phone: (02) 9515-6111
Fax: (02) 9515-9610

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Sleep and Circadian Research Group

Sleep and Circadian Research Group

Our Research

CIRUS, the Centre for Sleep and Chronobiology conducts patient-centred translational research across a broad spectrum of sleep disorders at the Woolcock Institute of Medical Research, University of Sydney and at partner sites within Sydney, across Australia and internationally.

The CIRUS research program is focused on understanding the impact of sleep disorders on health and well-being, and developing new diagnostic and therapeutic pathways to improve sleep health.

A sophisticated network of organisations, clinical services, research leaders and facilities allows CIRUS to conduct research in a range of areas through a multi-site collaborative approach, utilising the strengths of each partner. Our collective capacity and interdisciplinary methodology fosters new discoveries in science and medicine which are then translated to improved sleep healthcare.

Our group currently has funded programs in several key areas including impaired brain functioning in sleep disorders such as insomnia and sleep apnoea, shift work and productivity, disorders of the body clock and neurodegeneration and mental health.

Key Achievements

Over the last three years, CIRUS has worked to forge new ground in the understanding of the biology of sleep and the prevention and treatment of sleep disorders. Building on the work of the Centre for Integrated Research and Understanding of Sleep (National Health and Medical Research Council Centre of Research Excellence 2009-2013), CIRUS, the Centre of Sleep and Chronobiology at the Woolcock Institute of Medical Research has a diverse frontline research program.

Recent highlights for the CIRUS team include expanding our research facilities. In 2015, we established our Molecular Chronobiology unit and our Research Facility for High-density Electroencephalography Investigation. Both of these facilities allow our team to push the boundaries of sleep research in new directions.

Our shared research centres include NeuroSleep: The Centre for Translational Sleep and Circadian Neurobiology and The Co-operative Research Centre (CRC) for Alertness, Safety and Productivity. Both of these centres have a strong collaborative foundation. NeuroSleep, an NHMRC Centre of Excellence focuses on extending our knowledge of the neurobiology of sleep, the body's circadian system and the effects of sleep disorders on neurodegeneration. Meanwhile, the CRC for Alertness, Safety and Productivity has a strong focus on research translation through changes in policy, disease management and commercialisation.

CIRUS is actively working towards new diagnostic and treatment methods through the CRC Program as well as links with industry partners. In the end, the mission is to improve the sleep health of the community though our work.

Awards/Medals

  • Chapman, J. Ann Woolcock Training and Travel Award 2016, $7,500.
  • Dodds, K. Best poster award in her category 2016, Australasian Sleep Association Meeting, Adelaide.
  • D'Rozario, A. Best poster award in her category 2016, Australasian Sleep Association Meeting, Adelaide.
  • Gordon, C. Vice Chancellor's Awards for 2016, Outstanding Educational Engagement and Innovation, Health Collaboration Challenge project team.
  • Grunstein, R. Research Medal 2016, Thoracic Society of Australia and New Zealand.
  • Kempler, L. New Investigator Award 2016, Australasian Sleep Association Meeting, Adelaide.

Research Staff

  • Dr Dev Banerjee, Medical Director
  • A/Prof Delwyn Bartlett, Clinical Psychologist & Research Leader Sleep Health Psychology
  • Dr Chris Blackwell, Clinician Researcher
  • Dr Peter Buchanan, Clinician Researcher
  • Dr Elizabeth Cayanan, Post-Doctoral Research Fellow
  • Dr Julia Chapman, Post-Doctoral Research Fellow
  • Germaine Chau, Research Assistant
  • Garry Cho, Project Coordinator
  • Dr Maria Comas-Soberats, Research Fellow
  • Janet Chung, PhD Student, Pharmacist
  • Dr Pearl Chung, Clinician Researcher
  • Nathan Cross, PhD Student
  • Dr Angela D'Rozario, NHMRC-ARC Dementia Research Fellow & Research Leader Sleep Neurobiology
  • Kirsty Dodds, Clinical Care Coordinator
  • Paola Espinel Diaz, Research Manager
  • Dr Michelle Donegan, Research Dentist
  • Dr Shantel Duffy, NHMRC-ARC Dementia Research Development Fellow
  • Dr Carla Evans, Chief Senior Sleep Technologist
  • Emma Funnell, Research Administration Officer
  • Yael Galgut, Research Assistant
  • Dr Amanda Gamble, Clinician Researcher
  • Dr Christopher Gordon, Research Associate and Research Leader CRC Projects
  • Prof Ron Grunstein, NHMRC Senior Principal Research Fellow, Head CIRUS Sleep and Circadian Research Group
  • Parisa Hassan, Research Assistant
  • Dr Camilla Hoyos, NHMRC-ARC Dementia Research Fellow
  • Gagandeep Kaur, PhD Student, Pharmacist
  • Liora Kempler, PhD Student, Psychologist
  • Dr Roo Killick, Clinical Research Fellow
  • Dr Richard Lee, Clinician Researcher
  • Hong Man, Research Assistant
  • A/Prof Nathaniel Marshall, Research and Research Education, Research Leader Sleep Clinical Trials and Epidemiology
  • Dr Negar Memarian, Post-Doctoral Research Fellow
  • Dr Kerri Melehan, Research Associate
  • Dr Christopher Miller, Research Fellow
  • Anna Mullins, Lead Project Coordinator of Sleep Neurobiology, PhD Student
  • Haider Naqvi, PhD Student, Clinician
  • Darren O'Brien, Clinical and Research Operations Manager
  • Hannah Openshaw, Project Coordinator
  • Dr Craig Phillips, NHMRC Career Development Fellow, Research Leader Sleep Cardio-Metabolic Health
  • Dr Amanda Piper, Clinician Researcher
  • Diane Richards, Clinician Researcher
  • Luke Rowsell, PhD Student
  • A/Prof Bandana Saini, Pharmacist Researcher
  • Yasmina Serinel, PhD Student, Clinician
  • Dr Chris Seton, Clinician Researcher
  • Sheila Sivam, PhD Student
  • A/Prof Nick Stow, Clinician Researcher
  • Dr Jenny Theorell-Haglow, visiting Research Fellow
  • A/Prof David Wang, Senior Scientist
  • Dr Keith Wong, Senior Staff Specialist, Research Fellow
  • Dr Jong Won Kim, CCRE Post-Doctoral Fellow
  • A/Prof Brendon Yee, Senior Staff Specialist, Senior Research/Clinician Fellow

Higher Degree Students:

PhD:

  • Janet Chung
  • Nathan Cross
  • Yasmina Serinel
  • Gagandeep Kaur
  • Liora Kempler
  • Anna Mullins
  • Haider Naqvi
  • Luke Rowsell
  • Sheila Sivam

Masters:

  • Kirsty Dodds


Publications and Presentations

Publication Details:
  1. Adams, R.J., S.L. Appleton, A. Vakulin, C. Lang, S.A. Martin, A.W. Taylor, R.D. McEvoy, N.A. Antic, P.G. Catcheside, and G.A. Wittert, Association of daytime sleepiness with obstructive sleep apnoea and comorbidities varies by sleepiness definition in a population cohort of men. Respirology, 2016. 21(7): p. 1314-21.
  2. Ahmed, R.M., R.E. Newcombe, A.J. Piper, S.J. Lewis, B.J. Yee, M.C. Kiernan, and R.R. Grunstein, Sleep disorders and respiratory function in amyotrophic lateral sclerosis. Sleep Med Rev, 2016. 26: p. 33-42.
  3. Appleton, S.L., A. Vakulin, S.A. Martin, C.J. Lang, G.A. Wittert, A.W. Taylor, R.D. McEvoy, N.A. Antic, P.G. Catcheside, and R.J. Adams, Hypertension Is Associated With Undiagnosed OSA During Rapid Eye Movement Sleep. Chest, 2016. 150(3): p. 495-505.
  4. Appleton, S.L., A. Vakulin, G.A. Wittert, S.A. Martin, J.F. Grant, A.W. Taylor, R.D. McEvoy, N.A. Antic, P.G. Catcheside, and R.J. Adams, The association of obstructive sleep apnea (OSA) and nocturnal hypoxemia with the development of abnormal HbA1c in a population cohort of men without diabetes. Diabetes Res Clin Pract, 2016. 114: p. 151-9.
  5. Carter, S.G., M.S. Berger, J.C. Carberry, L.E. Bilston, J.E. Butler, B.k.Y. Tong, R.T. Martins, L.P. Fisher, D.K. McKenzie, R.R. Grunstein, and D.J. Eckert, 'Zopiclone Increases the Arousal Threshold without Impairing Genioglossus Activity in Obstructive Sleep Apnea'. Sleep 2016. 39(4): p. 757-66.
  6. Chapman, J., A. Vakulin, B. Yee, J. Hedner, and N. Marshall, Modafinil/Armodafinil in obstructive sleep apnoea: Systematic review and meta-analysis. ERJ, 2016. 47(5): p. 1420-8.
  7. Chapman, J.L., Y. Serinel, N.S. Marshall, and R.R. Grunstein, Residual Daytime Sleepiness in Obstructive Sleep Apnea After Continuous Positive Airway Pressure Optimization: Causes and Management. Sleep Med Clin, 2016. 11(3): p. 353-63.
  8. Cheung, J.M., D.J. Bartlett, C.L. Armour, J.G. Ellis, and B. Saini, People with insomnia: experiences with sedative hypnotics and risk perception. Health Expect, 2016. 19(4): p. 935-47.
  9. Cheung, J.M., D.J. Bartlett, C.L. Armour, and B. Saini, Treating Insomnia: A Review of Patient Perceptions Toward Treatment. Behav Sleep Med, 2016. 14(3): p. 235-66.
  10. Chowdhuri, S., S.F. Quan, F. Almeida, I. Ayappa, S. Batool-Anwar, R. Budhiraja, P.E. Cruse, L.F. Drager, B. Griss, N. Marshall, S.R. Patel, S. Patil, S.L. Knight, J.A. Rowley, and A. Slyman, An Official American Thoracic Society Research Statement: Impact of Mild Obstructive Sleep Apnea in Adults. Am J Respir Crit Care Med, 2016. 193(9): p. e37-54.
  11. Cross, N.E., C.M. Harrison, B.J. Yee, R.R. Grunstein, K.K. Wong, H.C. Britt, and N.S. Marshall, Management of Snoring and Sleep Apnea in Australian Primary Care: The BEACH Study (2000-2014). J Clin Sleep Med, 2016. 12(8): p. 1167-73.
  12. D'Rozario, A.L., Y. Galgut, and D.J. Bartlett, An Update on Behavioural Interventions for Improving Adherence with Continuous Positive Airway Pressure in Adults. Current Sleep Medicine Reports, 2016. 2(3): p. 166-179.
  13. Duffy, S.L., J. Lagopoulos, Z. Terpening, S.J.G. Lewis, R. Grunstein, L. Mowszowski, N. Cross, D. Hermens, I.B. Hickie, and S.L. Naismith, Association of anterior cingulate glutathione with sleep apnea in older adults Œat-risk for dementia. Sleep 2016. 39(4): p. 899-906.
  14. Espie, C.A., A.I. Luik, J. Cape, C.L. Drake, A.N. Siriwardena, J.C. Ong, C. Gordon, S. Bostock, P. Hames, M. Nisbet, B. Sheaves, G.F. R, D. Freeman, J. Costa-Font, R. Emsley, and S.D. Kyle, Digital Cognitive Behavioural Therapy for Insomnia versus sleep hygiene education: the impact of improved sleep on functional health, quality of life and psychological well-being. Study protocol for a randomised controlled trial. Trials, 2016. 17(1): p. 257.
  15. Fuller, J.M., K.K. Wong, C. Hoyos, I. Krass, and B. Saini, Dispensing good sleep health behaviours not pills--a cluster-randomized controlled trial to test the feasibility and efficacy of pharmacist-provided brief behavioural treatment for insomnia. J Sleep Res, 2016. 25(1): p. 104-15.
  16. Kaur, G., Y.L. Gan, C.L. Phillips, K. Wong, and B. Saini, Chronotherapy in practice: the perspective of the community pharmacist. Int J Clin Pharm, 2016. 38(1): p. 171-82.
  17. Kaur, G., C.L. Phillips, K. Wong, A.J. McLachlan, and B. Saini, Timing of Administration: For Commonly-Prescribed Medicines in Australia. Pharmaceutics, 2016. 8(2).
  18. Kaur, G., C.L. Phillips, K. Wong, and B. Saini, Awareness and attitudes of final-year pharmacy students towards chronotherapy: a needs analysis. Sleep and Biological Rhythms, 2016. 14(4): p. 329-338.
  19. Kempler, L., L. Sharpe, and D.J. Bartlett, Response to SMRV-D-15-564: Not yet time to throw the baby out with the bathwater, a paradigm shift is premature. Sleep Med Rev, 2016. 29: p. 119-20.
  20. Kempler, L., L. Sharpe, C.B. Miller, and D.J. Bartlett, Do psychosocial sleep interventions improve infant sleep or maternal mood in the postnatal period? A systematic review and meta-analysis of randomised controlled trials. Sleep Med Rev, 2016. 29: p. 15-22.
  21. Machaalani, R., C.A. Evans, and K.A. Waters, Objective adherence to positive airway pressure therapy in an Australian paediatric cohort. Sleep Breath, 2016. 20(4): p. 1327-1336.
  22. Magee, M., T.L. Stetten, S.A. Ferguson, R.R. Grunstein, C. Anderson, D.J. Kennaway, S.W. Lockley, and S.M.W. Rajaratnam, Associations between number of consecutive night shifts and impairment of neurobehavioral performance during a subsequent simulated night shift. Scandinavian Journal of Work Environment & Health, 2016. 42(3): p. 217-227.
  23. McEvoy, R.D., N.A. Antic, E. Heeley, Y. Luo, Q. Ou, X. Zhang, O. Mediano, R. Chen, L.F. Drager, Z. Liu, G. Chen, B. Du, N. McArdle, S. Mukherjee, M. Tripathi, L. Billot, Q. Li, G. Lorenzi-Filho, F. Barbe, S. Redline, J. Wang, H. Arima, B. Neal, D.P. White, R.R. Grunstein, N. Zhong, and C.S. Anderson, CPAP for Prevention of Cardiovascular Events in Obstructive Sleep Apnea. N Engl J Med, 2016. 375(10): p. 919-31.
  24. McKinnon, A.C., J. Lagopoulos, Z. Terpening, R. Grunstein, I.B. Hickie, J. Batchelor, S.J. Lewis, S. Duffy, J.M. Shine, and S.L. Naismith, Sleep disturbance in mild cognitive impairment is associated with alterations in the brain's default mode network. Behav Neurosci, 2016. 130(3): p. 305-15.
  25. Melehan, K.L., C.M. Hoyos, B.J. Yee, K.K. Wong, P.R. Buchanan, R.R. Grunstein, and P.Y. Liu, Increased sexual desire with exogenous testosterone administration in men with obstructive sleep apnea: a randomized placebo-controlled study. Andrology, 2016. 4(1): p. 55-61.
  26. Miller, C.B., D.J. Bartlett, A.E. Mullins, K.L. Dodds, C.J. Gordon, S.D. Kyle, J.W. Kim, A.L. D'Rozario, R.S. Lee, M. Comas, N.S. Marshall, B.J. Yee, C.A. Espie, and R.R. Grunstein, Clusters of Insomnia Disorder: An Exploratory Cluster Analysis of Objective Sleep Parameters Reveals Differences in Neurocognitive Functioning, Quantitative EEG, and Heart Rate Variability. Sleep, 2016. 39(11): p. 1993-2004.
  27. Murray, J.M., T.L. Sletten, M. Magee, C. Gordon, N. Lovato, D.J. Bartlett, D.J. Kennaway, L.C. Lack, R.R. Grunstein, S.W. Lockley, and S.M. Rajaratnam, Prevalence of Circadian Misalignment and Its Association with Depressive Symptoms in Delayed Sleep Phase Disorder. Sleep, 2016.
  28. Myles, H., N. Myles, N.A. Antic, R. Adams, M. Chandratilleke, D. Liu, J. Mercer, A. Vakulin, A. Vincent, G. Wittert, and C. Galletly, Obstructive sleep apnea and schizophrenia: A systematic review to inform clinical practice. Schizophr Res, 2016. 170(1): p. 222-5.
  29. Nguyen, C.D., J.W. Kim, R.R. Grunstein, C. Thamrin, and D. Wang, Respiratory Variability during Sleep in Methadone Maintenance Treatment Patients. J Clin Sleep Med, 2016. 12(4): p. 607-16.
  30. Phillips, C.L., C.M. Hoyos, B.J. Yee, and R.R. Grunstein, CrossTalk opposing view: Sleep apnoea causes metabolic syndrome. The Journal of Physiology, 2016. 594(17): p. 4691-4694.
  31. Phillips, C.L., C.M. Hoyos, B.J. Yee, and R.R. Grunstein, Rebuttal from Craig L. Phillips, Camilla M. Hoyos, Brendon J. Yee and Ronald R. Grunstein. J Physiol, 2016. 594(17): p. 4697-8.
  32. Pinheiro, M.B., K.K. Ho, M.L. Ferreira, K.M. Refshauge, R. Grunstein, J.L. Hopper, C.G. Maher, B.W. Koes, J.R. Ordonana, and P.H. Ferreira, Efficacy of a Sleep Quality Intervention in People With Low Back Pain: Protocol for a Feasibility Randomized Co-Twin Controlled Trial. Twin Res Hum Genet, 2016. 19(5): p. 492-501.
  33. Serinel, Y., B.J. Yee, R.R. Grunstein, K.H. Wong, P.A. Cistulli, H. Arima, and C.L. Phillips, Chronotherapy for hypertension in obstructive sleep apnoea (CHOSA): a randomised, double-blind, placebo-controlled crossover trial. Thorax, 2016.
  34. Sutherland, K., C.L. Phillips, B.J. Yee, R.R. Grunstein, and P.A. Cistulli, Maxillomandibular Volume Influences the Relationship between Weight Loss and Improvement in Obstructive Sleep Apnea. Sleep, 2016. 39(1): p. 43-9.
  35. Thomas, R.J., D. Wang, B.J. Yee, and R.R. Grunstein, Response to Brugniaux, Foster, and Beaudin. J Appl Physiol (1985), 2016. 121(1): p. 363.
  36. Vakulin, A., A. D'Rozario, J.W. Kim, B. Watson, N. Cross, D. Wang, A. Coeytaux, D. Bartlett, K. Wong, and R. Grunstein, Quantitative sleep EEG and polysomnographic predictors of driving simulator performance in obstructive sleep apnea. Clin Neurophysiol, 2016. 127(2): p. 1428-35.
  37. Wang, D., R.J. Thomas, B.J. Yee, and R.R. Grunstein, Last Word on Viewpoint: Hypercapnia is more important than hypoxia in the neuro-outcomes of sleep-disordered breathing. J Appl Physiol (1985), 2016. 120(12): p. 1489.
  38. Wang, D., R.J. Thomas, B.J. Yee, and R.R. Grunstein, Hypercapnia is more important than hypoxia in the neuro-outcomes of sleep-disordered breathing. J Appl Physiol (1985), 2016. 120(12): p. 1484.
  39. Yang, M.Y., J. Verschuer, Y. Shi, Y. Song, A. Katsifis, S. Eberl, K. Wong, J.D. Brannan, W. Cai, W.H. Finlay, and H.K. Chan, The effect of device resistance and inhalation flow rate on the lung deposition of orally inhaled mannitol dry powder. Int J Pharm, 2016. 513(1-2): p. 294-301.

Presentations:
  1. Bartlett, D. Oral Presentation: 'Individual and group treatment of insomnia at the Woolcock Institute, Sydney'. Sleep DownUnder 2016, Adelaide, Oct 2016.
  2. Bartlett, D. Session: 'Education and prevention: sleep education for new parents'. Sleep DownUnder 2016, Adelaide, Oct 2016.
  3. Carter, S., Carberry, J., Fisher, L., Cho, G., Rollo, C., Stevens, D., D'Rozario, A., McKenzie, D., Grunstein, R., Eckert, D. New Investigator Presentation: 'Effects of one month of nightly zopiclone on obstructive sleep apnoea severity and measures of alertness: A randomised controlled trial'. Sleep DownUnder 2016, Adelaide, Oct 2016.
  4. Cayanan, E., Hoyos, C., Djavadkhani, Y., Wong, K., Yee, B., Phillips, C., Marshall, N., Grunstein, R. Presentation: 'Effectiveness Of Two Maintenance Diets Following A Very Low Energy Diet To Reduce Cardio-metabolic Risk In Obese Sleep Apnea Patients: A Randomised Controlled Trial. International Congress on Obesity 2016, Vancouver, Canada, May 2016.
  5. Chang, Y., Wong, K., Yee, B., Hoyos, C., Sullivan, D., Grunstein, R., Phillips, C. Oral Presentation: 'The effect of CPAP therapy on levels of Troponin and pro-BNP in patients with obstructive sleep apnoea: A randomised controlled trial'. Sleep DownUnder 2016, Adelaide, Oct 2016.
  6. Chapman, J., Cayanan, E., Hoyos, C., Serinel, Y., Yee, B., Wong, K., Grunstein, R., Marshall, N. Oral Presentation: 'Diet, exercise and armodafinil for obstructive sleep apnea patients unable to tolerate standard treatments (DEAR). A randomised, parallel group, placebo-controlled trial'. Sleep DownUnder 2016, Adelaide, Oct 2016.
  7. Chapman, J., Hoyos, C. Early Career Seminar: 'Sound clinical trials practice part 2: Practical tips'. Sleep DownUnder 2016, Adelaide, Oct 2016.
  8. Chapman, J., Cayanan, E., Hoyos, C., Serinel, Y., Yee, B., Wong, K., Grunstein, R., Marshall, N. Presentation: 'Diet, exercise and armodafinil for obstructive sleep apnea patients unable to tolerate standard treatments (DEAR): A randomised, parallel group, placebo-controlled trial'. Congress of the European Sleep Research Society 2016, Bologna, Italy, September 2016.
  9. Comas, M., Gan, R., Grunstein, R., Lewis, S. Poster: 'Time for translational molecular chronobiology in Parkinson's disease'. Sleep DownUnder 2016, Adelaide, Oct 2016.
  10. Cross N., Terpening Z., D'Rozario, A., Duffy, S., Kim, J.W., Lewis, S., Grunstein, R., Naismith, S. Poster: 'Slow spindles during afternoon napping are important for memory consolidation in patients with mild cognitive impairment'. 1st International Conference on Sleep Spindling, Budapest, Hungary, May 2016.
  11. Dodds, K., Miller, C., Kyle, S., Marshall, N., Gordon, C. Poster: 'The beat up on heart rate variability in insomnia patients: A critical literature review'. Sleep DownUnder 2016, Adelaide, Oct 2016.
  12. D'Rozario, A., Hoyos, C., Won Kim, J., Vakulin, A., Wong, K., Leow, J., Bartlett, D., Grunstein, R. Poster: 'Sleep spindle density increases with six months of continuous positive airway pressure (CPAP) treatment and correlates with improved neurobehavioural function in obstructive sleep apnea (OSA)'. Sleep DownUnder 2016, Adelaide, Oct 2016.
  13. D'Rozario, A., Hoyos, C., Wong, K., Won Kim, J., Kim, D., Field, C., Vakulin, A., Grunstein, R., Bartlett, D. Oral Presentation: 'Six months of continuous positive airway pressure (CPAP) treatment improves neurobehavioural function and quantitative sleep electroencephalographic (EEG) parameters in obstructive sleep apnea'. Sleep DownUnder 2016, Adelaide, Oct 2016.
  14. D'Rozario, A. Symposia: 'Neurophysiology (EEG) insights into cognitive deficits in sleep disorders and neurodegenerative disease'. Sleep DownUnder 2016, Adelaide, Oct 2016.
  15. Fong, M., Caterson, I., Theorell-Haglow, J., Grunstein, R., Hoyos, C., Phillips, C. Presentation: 'The Effect Of Shift Work On Postprandial Metabolism And Food Desirability: Study Protocol'. International Congress on Obesity 2016, Vancouver, Canada, May 2016.
  16. Galgut, Y., Wong, K., Lobsey, J., Hall, T., Collier, J., Pearson, J., Rutherford, D., Bartlett, D. Oral Presentation: 'Cognitive behavioural therapy for insomnia administered by practice nurses In rural NSW'. Sleep DownUnder 2016, Adelaide, Oct 2016.
  17. Kempler, L., Sharpe, L., Bartlett, D. New Investigator Presentation: 'Brief sleep psychoeducation program improves sleep quality and reduces insomnia symptoms in new mothers'. Sleep DownUnder 2016, Adelaide, Oct 2016.
  18. Marshall, N. Early Career Seminar: 'Sound clinical trials practice part 1: Overview and key principles'. Sleep DownUnder 2016, Adelaide, Oct 2016.
  19. Miller, C., Valenti, L., Harrison, C., Britt, H., Bartlett, D., Glozier, N., Cross, N., Grunstein, R., Marshall, N. Oral Presentation: 'Primary care management of insomnia in Australia: The BEACH study (2000-15)'. Sleep DownUnder 2016, Adelaide, Oct 2016.
  20. Miller, C.B., Rae, C.D., Green, M., Yee, B.J., Gordon, C.J, D'Rozario, A.L., Kyle, S.D., Espie, C.A., Grunstein, R.R. Bartlett, D.J. Oral Presentation: 'A severe objective short-sleep insomnia disorder phenotype is associated with reduced brain creatine levels and impaired metabolism: an in vivo magnetic resonance spectroscopy assessment'. Presented at the 30th Anniversary Meeting of the Associated Professional Sleep Societies, Denver, U.S.A. June 2016.
  21. Miller, C.B., Bartlett, D.J., Mullins, A.E., Dodds, K.L., Gordon, C.J, Kyle, S.D., Kim, J.W., D'Rozario, A.L., Lee, R.S.C., Marshall, N., Yee, B.J., Espie, C.A., Grunstein, R.R. Oral Presentation: 'The Insomnia 100 Study: Phenotypes of Insomnia Disorder built from cluster analysis of objective sleep parameters reveal differences in neurocognitive functioning, quantitative EEG and heart rate variability'. Presented at the 30th Anniversary Meeting of the Associated Professional Sleep Societies, Denver, U.S.A. June 2016.
  22. Mullins, A., D'Rozario, A., Cross, N., Won Kim, J., Marshall, N., Bartlett, D., Grunstein, R. Poster: 'Sleep spindle characteristics before and after sleep deprivation in obstructive sleep apnea'. Sleep DownUnder 2016, Adelaide, Oct 2016.
  23. Mullins, Anna. Oral presentation: 'Sleep Spindle Characteristics before and after sleep deprivation in obstructive sleep apnea'. 1st International Conference on Sleep spindling. Budapest, Hungary, May 2016.
  24. Osman, A., Nguyen, C., Carberry, J., Burke, P., Wijesuriya, N., Tong, Benjamin., Grunstein, R., Eckert, D. Oral Presentation: 'Awake upper airway collapsibility is related to airway collapsibility during sleep (Pcrit) in obstructive sleep apnoea'. Sleep DownUnder 2016, Adelaide, Oct 2016.
  25. Phillips, C. Symposia: 'Treating OSA to improve AF management - what is the evidence?'. Sleep DownUnder 2016, Adelaide, Oct 2016.
  26. Rowsell, L., Yee, B., Wong, K., Somogyi, A., Eckert, D., Grunstein, R., Wang, D. New Investigator Presentation: 'The pharmacogenomics of morphine effect on obstructive sleep apnea: A randomised double-blind placebo-controlled crossover trial'. Sleep DownUnder 2016, Adelaide, Oct 2016.
  27. Schembri, R., Baleviani, H., D'Rozario, A., Bartlett, D., Mullins, A., Won Kim, J., Barnes, M., Jackson, M. Poster: 'Slow wave activity In obstructive sleep apnoea and depression'. Sleep DownUnder 2016, Adelaide, Oct 2016.
  28. Sletten, T., Magee, M., Murray, J., Gordon, C., Lovato, N., Kennaway, D., Bartlett, D., Lockley, S., Lack, L., Grunstein, R., Rajaratnam, S. Oral Presentation: 'Melatonin for improving sleep initiation and daytime impairments in Delayed Sleep Phase Disorder'. Sleep DownUnder 2016, Adelaide, Oct 2016.
  29. Stevens, D., Vakulin, D., Openshaw, H., D'Rozario, A., Wong, K., Catcheside, P., McEvoy, D., Grunstein, R. Poster: 'The utility of clinical variables for identifying OSA patients vulnerable to working memory impairment during extended wakefulness'. Sleep DownUnder 2016, Adelaide, Oct 2016.
  30. Vakulin, A., Cheung, H., Stevens, D., Arciuli, J., Won Kim, J., Leow, J., Rae, C., Wong, K., Saini, B., Grunstein, R., D'Rozario, A. Poster: 'Sleep spindle activity significantly correlates with implicit memory consolidation in obstructive sleep apnoea (OSA)'. Sleep DownUnder 2016, Adelaide, Oct 2016.
  31. Wang, D. Oral Presentation: 'Effects of morphine on awake ventilatory control and OSA severity'. Sleep DownUnder 2016, Adelaide, Oct 2016.

Research Grants

GRANTING BODY AWARDEES PROJECT TITLE YEARS total $$ Years
Mason Foundation Grunstein, R., Hickie, I., Jackson, M.  Extreme phenotyping in patients with non-restorative sleep (NRS) – is there a “neuromarker” for CFS/SEID   $79,895 2016
NHMRC Postgraduate Scholarship Djavadkhani, Y.  Chronotherapy for hypertension in obstructive sleep apnoea   $48,028 2016-2017
USYD Sydney Medical School Kick Start Grants Program  Miller, C.  Sleep Restriction Therapy (SRT) for chronic insomnia disorder: physiological, cognitive & objective sleep alterations after six weeks of therapy intervention - a pilot study   $22,375 2016
NHMRC Senior Principal Research Fellowship  Grunstein, R.  Addressing Therapeutic Challenges in Sleep Disorders   $900,000 2016-2020
NHMRC Targeted Research  Marks, G., Grunstein, R., Tonin, R., Marshall, N., Welgampola, M., Glozier, N., Phillips, C., Toelle, B., Bartlett, D., Cowie, C.  Multidimensional Assessment of the Health Impacts of Infrasound: Two Randomised Controlled Trials   $1,943,933 2016-2020
NHMRC ARC Dementia Research Development D’Rozario, A.  Sleep, plasticity and neurodegeneration: Targeting sleep to improve cognitive in Mild Cognitive Impairment (MCI)   $525,116 2016-2020
NHMRC ARC Dementia Research Development Hoyos, C.  Sleep-wake disturbances and cardio-metabolic dysfunction in at risk dementia: a novel pathway in neurocognitive decline   $558,304 2016-2020

Contact details for department

Head of Department: Professor Ron Grunstein

Department/Unit: Sleep and Circadian Research Group
Address:
431 Glebe Point Road
Glebe NSW 2037
Telephone: (02) 9114 0438
Facsimile: (02) 9114 0014
Web: http://woolcock.org.au/sleep-research
Email: emma.funnell@sydney.edu.au