Our Research

Our Research

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Contact Details

  Street address:
Level 11, KGV Building
Missenden Road
CAMPERDOWN NSW 2050
 
Postal address:
Post Office Box M30
Missenden Road NSW 2050

Phone: (02) 9515-6111
Fax: (02) 9515-9610

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Renal Medicine

Our Research

The Department of Renal Medicine and Transplantation has a range of ongoing research projects spanning from basic science (immunology of kidney transplant rejection and kidney disease), through clinical trials (immunosuppression in kidney transplantation, diabetes after transplantation, new therapies in kidney disease), policy and practice (cost of chronic kidney disease, patient relevant outcomes, burden of diabetic nephropathy, access to kidney transplantation) to health outcomes (long-term outcomes after kidney transplantation, cancer after transplantation, disease recurrence). Our goals are to pursue new advances in understanding, preventing and managing kidney disease with the aim of easing the burden that kidney disease imparts upon our patients and our society.

Research Staff

  • Prof Steve Chadban
  • A/Prof David Gracey
  • Dr Paul Snelling
  • A/Prof Kate Wyburn

Publications and Presentations

Publication Details:

Professor Steve Chadban:

  1. Ralph AF, Butow P, Hanson CS, Chadban SJ, Chapman JR, Craig JC, Kanellis J, Luxton G, Tong A. Donor and Recipient Views on Their Relationship in LivingKidney Donation: Thematic Synthesis of Qualitative Studies. Am J Kidney Dis. 2016 Nov 23. pii: S0272-6386(16)30563-7.
  2. Clayton PA, Lim WH, Wong G, Chadban SJ. Relationship between eGFR Decline and Hard Outcomes after Kidney Transplants. J Am Soc Nephrol. 2016 Nov;27(11):3440-3446.
  3. Chadban SJ. Josette Marie Eris April 7, 1959 to April 6, 2016 TTS Councilor and Professor. Transplantation. 2016 Aug;100(8):1596.
  4. Lopez-Vargas PA, Tong A, Howell M, Phoon RK, Chadban SJ, Shen Y, Craig JC. Patient awareness and beliefs about the risk factors and comorbidities associated with chronic kidney disease - a mixed-methods study. Nephrology (Carlton). 2016 Jun 1. doi: 10.1111/nep.12829. [Epub ahead of print]
  5. Wyld ML, Chadban SJ, Morton RL. Improving Our Understanding of Quality of Life in CKD. Am J Kidney Dis. 2016 Jun;67(6):820-1.
  6. Clayton PA, Saunders JR, McDonald SP, Allen RD, Pilmore H, Saunder A, Boudville N, Chadban SJ. Risk-Factor Profile of Living Kidney Donors: The Australia and New Zealand Dialysis and Transplant Living Kidney Donor Registry 2004-2012. Transplantation. 2016 Jun;100(6):1278-83.
  7. Kwan TK, Chadban SJ, Wu H. Toll-Like Receptor 4 Deficiency Improves Short-term Renal Function but not Long-term Graft Survival in a Fully MHC-Mismatched Murine Model of Renal Allograft Transplantation. Transplantation. 2016 Jun;100(6):1219-27.
  8. Clayton PA, Lim WH, Wong G, Chadban SJ. Relationship between eGFR Decline and Hard Outcomes after Kidney Transplants. J Am Soc Nephrol. 2016 Apr 8. pii: ASN.2015050524. [Epub ahead of print] PubMed PMID: 27059513.
  9. Braza F, Brouard S, Chadban S, Goldstein DR. Role of TLRs and DAMPs in allograft inflammation and transplant outcomes. Nat Rev Nephrol. 2016 May;12(5):281-90.
  10. Pilmore H, Chadban S. Cardiac Screening for Kidney Transplantation: The Clinical Conundrum Continues. Transplantation. 2016 Mar;100:1396-7
  11. Barr E, Reutens A, Magliano D, Wolfe R, Lu Z, Sikaris K, Tanamas S, Atkins R, Chadban S, Shaw J, Polkinghorne K. Cystatin C estimated glomerular filtration rate and all-cause and cardiovascular disease mortality risk in the general population: AusDiab study. Nephrology (Carlton). 2016 Mar 3. doi: 10.1111/nep.12759. [Epub ahead of print] PubMed PMID: 26938304.
  12. Wyld ML, Chadban SJ. Recurrent IgA Nephropathy After Kidney Transplantation. Transplantation. 2016 Feb 18. [Epub ahead of print] PubMed PMID: 26895219.
  13. Ralph AF, Alyami A, Allen RD, Howard K, Craig JC, Chadban SJ, Irving M, Tong A. Attitudes and beliefs about deceased organ donation in the Arabic-speaking community in Australia: a focus group study. BMJ Open. 2016 Jan 19;6(1):e010138. doi: 10.1136/bmjopen-2015-010138. PubMed PMID: 26787253; PubMed Central PMCID: PMC4735320.
  14. Lim WH, Chadban SJ. Cancer in ESRD: Clear on the Epidemiology, Hazy on the Mechanisms. J Am Soc Nephrol. 2016 May;27(5):1272-5. doi: 10.1681/ASN.2015091021. Epub 2015 Nov 12. PubMed PMID: 26563385
  15. Other: ISN Sister Renal Centre Zimbabwe - RPA

A/Prof David Gracey:

  1. Kakar S, Drak D, Amin T, Cheung J, O'Connor C, Gracey D. Screening and management of risk factors for cardiovascular disease in HIV-positive patients attending an Australian urban sexual health clinic. Sex Health. 2016 Nov 11. doi: 10.1071/SH16106. [Epub ahead of print] PubMed PMID: 27832579.

Dr Paul Snelling:

  1. Zhang L, Badve SV, Pascoe EM, Beller E, Cass A, Clark C, de Zoysa J, Isbel NM, Liu X, McTaggart S, Morrish AT, Playford G, Scaria A, Snelling P, Vergara LA, Hawley CM, Johnson DW. REPRESENTATIVENESS OF HONEYPOT TRIAL PARTICIPANTS TO AUSTRALASIAN PD PATIENTS. Perit Dial Int. 2016 Dec 1. pii: pdi.2016.00065. doi: 10.3747/pdi.2016.00065. [Epub ahead of print] PubMed PMID: 27935534.
  2. Morton RL, Webster AC, McGeechan K, Howard K, Murtagh FE, Gray NA, Kerr PG, Germain MJ, Snelling P. Conservative Management and End-of-Life Care in an Australian Cohort with ESRD. Clin J Am Soc Nephrol. 2016 Dec 7;11(12):2195-2203. Epub 2016 Oct 3. PubMed PMID: 27697783; PubMed Central PMCID: PMC5142079.
  3. Roberts MA, Pilmore HL, Ierino FL, Badve SV, Cass A, Garg AX, Isbel NM, Krum H, Pascoe EM, Perkovic V, Scaria A, Tonkin AM, Vergara LA, Hawley CM; BLOCADE Study Collaborative Group.. The β-Blocker to Lower Cardiovascular Dialysis Events (BLOCADE) Feasibility Study: A Randomized Controlled Trial. Am J Kidney Dis. 2016 Jun;67(6):902-11. doi: 10.1053/j.ajkd.2015.10.029. Epub 2015 Dec 22. PubMed PMID: 26717861.

A/Prof Kate Wyburn:

  1. Lo P, Sharma A, Craig JC, Wyburn K, Lim W, Chapman JR, Palmer SC, Strippoli GF, Wong G. Preconditioning Therapy in ABO-Incompatible Living Kidney Transplantation: A Systematic Review and Meta-Analysis. Transplantation. 2016 Apr;100(4):933-42

Dr John Saunders:

  1. Clayton PA, Saunders JR, McDonald SP, Allen RD, Pilmore H, Saunder A, Boudville N, Chadban SJ. Risk-Factor Profile of Living Kidney Donors: The Australia and New Zealand Dialysis and Transplant Living Kidney Donor Registry 2004-2012. Transplantation. 2016 Jun;100(6):1278-83. doi: 10.1097/TP.0000000000000877. PubMed PMID: 27123877.
  2. Smyth B, Jones C, Saunders J. Prescribing for patients on dialysis. Aust Prescr. 2016 Feb;39(1):21-4. doi: 10.18773/austprescr.2016.008. Epub 2016 Feb 1. Review. PubMed PMID: 27041803; PubMed Central PMCID: PMC4816865.

Research Grants

GRANTING BODY AWARDEES PROJECT TITLE YEARS total $$ Years
USyd “Near Miss” funding S. Chadban (CIA), H Wu “Manipulating the Microbiome to achieve transplant tolerance”.   $30,000 2017
LifePlan project grant D. Gracey A national program to improve the approach to kidney disease in HIV-infected patients in Australasia. Funding ongoing $75,000 p.a $150,000 2012-2014
Other   TTS Sister Centre in Kidney Transplantation: Hospital Kuala Lumpor $10,000  

Contact details for department

Head of Department: Professor Steve Chadban

Department/Unit: Renal Medicine
Address:
RPA Hospital
Missenden Road
Camperdown NSW 2050
Telephone: (02) 9515 6600
Facsimile: (02) 9515 6329
Web: www.slhd.nsw.gov.au/research/
Email: steve.chadban@health.nsw.gov.au