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Contact Details

  Street address:
Level 11, KGV Building
Missenden Road
CAMPERDOWN NSW 2050
 
Postal address:
Post Office Box M30
Missenden Road NSW 2050

Phone: (02) 9515-6111
Fax: (02) 9515-9610

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Department of Endocrinology

Our Research

The RPAH Department of Endocrinology, in addition to inpatient care, comprises three clinical Units and two laboratory services. These are:

  • The Diabetes Centre
  • Endocrinology and Metabolism Unit
  • Metabolism and Obesity Service, and the
  • Endocrinology Research Laboratory and Endocrinology Diagnostic Laboratory

In addition, the Endocrinology Node of the Charles Perkins Centre commenced in 2015. These Units, are each reported upon below in the combined Research Activity Report.

The research undertaken is broad in scope, reflecting the breadth of Endocrine related disease. Major diseases studied are diabetes and its complications, thyroid disease including cancer, pituitary disease and morbid obesity. The research undertaken includes clinical intervention studies, clinical audit and health care delivery research, and translational research including biomarker studies and testing of findings and potential mediators of disease in preclinical models. Organised external educational activities, for example through Webinars, also occurs.

Key Achievements

Continuation in support of series of postgraduate students (11 higher degree students), and high quality publications (30 in total), including in specific research themes in Endocrinology.

Awards/Medals

  • Dr Arianne Sweeting Endocrine Society of Australia Travel Grant Annual Scientific Meeting, 2016
  • Dr Albert Hsieh Endocrine Society of Australia Travel Grant Annual Scientific Meeting, 2016
  • Anh Tao ADS Travel Grant Annual Scientific Meeting, 2016
  • Anh Tao PRSS Award, University of Sydney 2016
  • Babu Raja Maharjan PRSS Award, University of Sydney 2016
  • Babu Raja Maharjan ADS Travel Grant Annual Scientific Meeting, 2016
  • Dr Angela Lee, Best Clinical Research Poster Award ADS/ADEA Annual Scientific Meeting, 2016.

Research Staff

  • Professor Stephen Twigg : Head, Dept of Endocrinology
  • A/Professor Susan McLennan: Principal Hospital Scientist
  • A/Professor Paul Williams: Principal Hospital Scientist
  • Dr Danqing Min: Senior Hospital Scientist and Senior Research Fellow
  • Dr Catherine Woolnough: Hospital Scientist
     
  • Clinical Associate Professor Jencia Wong: Director of Research, Diabetes Centre
  • Dr Ted Wu: Director of Diabetes Centre
  • Clinical Associate Professor Glynis Ross
  • Emeritus Professor Dennis Yue
  • Dr Lisa Simmons: H-JMO & Endocrinologist
  • Dr Angela Lee: Honorary Medical Officer & PhD student
  • Dr Tim Middleton: Honorary Medical Officer & PhD student
  • Associate Professor Belinda Brooks: Team Leader of Research & Clinical Trials
  • Mrs Maria Constantino: Data Manager
  • Ms Lynda Molyneaux: Statistician
  • Associate Professor Jane Overland: Nurse Practitioner
  • Associate Professor Marg McGill: Assistant Director Diabetes Centre
  • Ms Ellen Landy, Ms Amanda Gauld, & Ms Charmaine
    Griffiths, Ms Rebecca Denner: Research nurse, Study Coordinators
  • Dr Turki Almogbel: Visiting Fellow, Kingdom of Saudi Arabia
     
  • A/Prof Elizabeth Chua, Director Endocrinology & Metabolism Centre
  • Dr Ash Gargya, Staff Specialist
  • Dr Nimalie Perera, Honorary Medical Officer
  • Dr Albert Hsieh, Honorary Medical Officer & PhD student
  • Dr Arianne Sweeting, PhD student
  • Ms Julie Hetherington, Nurse Practitioner, CNC, Endocrinology & Metabolism Centre
  • Ms Krisztina Toth, RN, Endocrinology & Metabolism Centre
  • A/Prof. Tania Markovic, Director Metabolism and Obesity Services
  • Ms Elisia Manson, CNC, Metabolism and Obesity Services
  • Dr Janet Franklin
  • Ms Georgina Loughnan

Higher Degree Students:

PhD:

  • Dr Albert Hsieh, (PhD, "Antibody-mediated endocrine diseases", University of Sydney)
    Supervisors: Prof SM Twigg, A/P EL Chua, A/Prof SV McLennan, A/Prof PF Williams, A/Prof S Adelstein
  • Dr Tripti Joshi, (PhD, "Thyroid cancer in New Caledonia", University of Sydney) Supervisors: A/P EL Chua, Prof S McLennan
  • Ms Anh Tao, (PhD, Understanding the dysregulation of matrix metalloproteinases (MMPs) in the progression of diabetic kidney disease: Detection of early changes may serve as crucial biomarkers for preventive measures of disease, University of Sydney), Supervisors: A/Prof SV McLennan, Dr D Min
  • Linda Ban, (PhD, Extracellular vesicles in non-alcoholic fatty liver disease pathogenesis, University of Sydney), Supervisors: A/Prof SV McLennan, Prof Nicholas Shackel
  • Babu Raja Maharjan. (PhD, An Investigation of the Effect of Diet and Exercise on Adipose Tissue Function in Different Fat Depots, University of Sydney), Supervisors: A/Prof Paul Williams, A/Prof SV McLennan, Professor Stephen Twigg
  • Ms Maria Constantino. PhD Supervisors A/Prof J Wong, Professor Emeritus DK Yue)
  • Dr Agata Piotrowicz. An online tool to prevent hypoglycaemia related to exercise in adults with type 1 diabetes PhD Supervisors Prof SM Twigg, A/Professor M McGill
  • Dr Angela Lee. Metabolic syndrome and Exercise in adults with type 1 diabetes PhD Supervisors Prof SM Twigg, A/Professor J Wong, A/Professor Jeff Flack Dr Nathan Johnson.
  • Mr Sergio Francisco Martinez Huenchullan Exercise and Obesity Interactions.  PhD Supervisors Prof SM Twigg, A/Professor Charmaine Tam, A/Professor Susan McLennan. 
  • Dr Arianne Sweeting (PhD, Early Gestational Diabetes Prediction and Outcomes, University of Sydney), Supervisors: Professor Jon Hyett, A/Prof J Wong, A/Prof GP Ross
  • Jovana Mijatovic (PhD, A Randomised controlled trial (RCT) examining the effect of a modestly lower carbohydrate diet on plasma ketone levels in women with gestational diabetes mellitus (GDM). University of Sydney), Supervisors: Professor Jennie Brand-Miller, A/Prof GP Ross
  • Dr Angela Lee (current full-time PhD candidate, Type 1 diabetes and the metabolic syndrome University of Sydney). Primary supervisor: Prof Stephen Twigg, Associate supervisors: A/Prof Jencia Wong, Prof Jeff Flack, Dr Nathan Johnson
  • Dr Timothy Middleton (PhD, Determinants and Modifiers of Renal Outcomes in Young Adult Onset Type 2 Diabetes, University of Sydney). Supervisors: A/Prof J Wong, Prof SM Twigg, Prof DK Yue

Masters:

  • Dr Joel Hardman, (Master of Philosophy Medicine, "Genetic Changes in Thyroid Nodules and in Patients with Thyroid Cancer", University of Sydney), Supervisors: Prof S McLennan, A/P Michael Elliott, A/P EL Chua


Publications and Presentations

Publication Details:
  1. Gibson AA, Seimon RV, Franklin J, Markovic TP, Byrne N, Manson E, Caterson ID, Sainsubry A. Slow versus fast weight loss: development process and rationale of the dietary interventions for the TEMPO Diet Trial - under second review- Obesity Science & Practice 2016 Jun;2(2):162-173.
  2. Kirzirian N, Kong Y, Muirhead R, Overs S, Garnett S, Petocz P, Sim K, Celermajer D, Louie J, Markovic TP, Ross G, Ward L, Brand-Miller J, Skilton M The effects of a low glycemic index diet during pregnancy on offspring growth, body composition and vascular health., American Journal of Clinical Nutrition, pub on line March 2, 2016 DOI:10.3945/ajcn.115.123695.
  3. Armaghanian N, Brand-Miller JC, Markovic TP, Steinbeck KS. Hypoglycaemia in cystic fibrosis in the absence of diabetes: a systematic review. Journal of Cystic Fibrosis, March 2016, DOI: 10.1016/j.jcf.2016.02.012.
  4. Kirzirian N, Markovic TP, Muirhead R, Brodie S, Garnett S Louie, J, Petocz P, Ross G, Brand-Miller J . Macronutrient Balance and Dietary Glycemic Index in Pregnancy Predict Neonatal Body Composition.. Nutrients May 2016: 8(5);270.
  5. Gibson AA, Franklin J, Pattinson AL, Cheng ZGY, Samman S, Markovic TP, Sainsbury A.  Comparison of Very Low Energy Diet products available in Australia, and how to tailor them to optimise protein content for younger and older adult men and women.. Healthcare, 4, 71; 2016, DOI: 10.3390/healthcare4030071.
  6. Nielssen O, Chudleigh A, Chen M, Large M, Markovic TP, Cooper L. Results of a metabolic health clinic at a hostel for homeless men. 2016, Australasian Psychiatry (in press)
  7. Gargya A, Cooper M, Hetherington J, Sommers K, Chua E. Acute adrenal insufficiency: an aide-memoire of the critical importance of its recognition and prevention. Internal Medicine Journal 2016 Mar; 46(3): 356-9;
  8. Bittoun R, Gargya A, Mann L. Weight gain, hypothyroidism and smoking cessation. Journal of Smoking Cessation. doi:10.1017/jsc.2016.13;
  9. Matthews T, Chua E, Gargya A, Clark J, Elliott M. Elevated serum thyroglobulin levels at the time of ablative radioactive iodine therapy indicate a worse prognosis in thyroid cancer: An Australian retrospective cohort study. Journal of Otology and Laryngology. Jul 2016; 130(S4): S50-53.
  10. Tabet E, Gargya A. Subclinical thyroid disease: when to treat? Endocrinology Today 2016; 5(3): 25-30.
  11. Lomax A, Sweeting A, Lim J, Cheng R, McGill N, Lowe P, Shackel N, McNeil C, Chua E. Metastatic Melanoma and Pembrolizumab Toxicity in a Real-World Setting: Practical Management of Common Toxicities. Asia-Pacific Journal of Clinical Oncology 2016; 12:60-60.
  12. Meng XX, Xu HX, Yao M, Dong Q, Zhang XD. Implication of Unfolded Protein Response and Autophagy in the Treatment of BRAF Inhibitor Resistant Melanoma. Anticancer Agents Med Chem. 2015 Sep 29. Anticancer Agents Med Chem. 2016;16(3):291-8.
  13. Xi Z, Yao M, Li Y, Xie C, Holst J, Liu T, Cai S, Lao Y, Dong Q. Guttiferone K impedes cell cycle re-entry of quiescent prostate cancer cells via stabilization of FBXW7 and subsequent c-MYC degradation, Cell Death and Disease,2016; 7 (6): 1-13.
  14. Shen K, Xi Z, Xie J, Wang H, Xie C, Lee C, Fahey P, Dong Q, Xu H, 2016, Guttiferone K suppresses cell motility and metastasis of hepatocellular carcinoma by restoring aberrantly reduced profilin 1, Oncotarget, 2016, vol 7, no 35, pp 56650-56663.
  15. Min D, Brooks B, Wong J, Aamidor S, Seehoo R, Sutanto S, Harrisberg B, Yue DK, Twigg SM, and McLennan SV. Monocyte CD163 is altered in association with diabetic complications: possible protective role. J Leukoc Biol 2016: Vol.100 (6), pp1375-1383.
  16. Januszewki AS, Surya S, McLennan S, O'Neal DN, Keech AC, Twigg SM, Jenkins AJ. Shorter telomere in adults with Type 1 diabetes correlate with diabetes duration, but only weakly with vascular function and risk factors. Diabetes Res Clin Pract. 2016 Jul;117:4-11. doi: 10.1016/j.diabres.2016.04.040. Epub 2016.
  17. Ban LA, Shackel NA, McLennan SV. Extracellular Vesicles: A New Frontier in Biomarker Discovery for Non-Alcoholic Fatty Liver Disease. International Journal of Molecular Sciences .March 2016:17(3):376.
  18. Lee AS, Brooks BA, Simmons L, Kilborn MJ, Wong J, Twigg SM & Yue DK. Hypoglycaemia and QT interval prolongation: detection by simultaneous Holter and continuous glucose monitoring. Diabetes Res Clin Pract. 2016; 113: 211-214.
  19. Rudland VL, Hinchcliffe M, Pinner J, Cole S, Mercorella B, Molyneaux L, Constantino M, Yue DK, Ross GP, Wong J. Identifying Glucokinase Monogenic Diabetes in a Multiethnic Gestational Diabetes Mellitus Cohort: New Pregnancy Screening Criteria and Utility of HbA1c. Diabetes Care. 2016 Jan;39(1):50-2
  20. Constantino MI, Al-Saeed AH, Molyneaux L et al.  An inverse Relationship Between Age of Type 2 Diabetes Onset and Complication Risk and Mortality:  The Impact of Youth-Onset Type 2 Diabetes.  Diabetes Care 2016, 9(5): 823-829.
  21. Sweeting AN, Ross GP, Hyett J, Molyneaux L, Constantino M, Harding AJ, Wong J. Gestational Diabetes Mellitus in Early Pregnancy: Evidence for Poor Pregnancy Outcomes Despite Treatment. Diabetes Care. 2016 Jan;39(1):75-81
  22. Min D, Brooks B, Wong J, Aamidor S, Seehoo R, Sutanto S, Harrisberg B, Yue DK, Twigg SM, McLennan SV Monocyte CD163 is altered in association with diabetic complications: possible protective role. J Leukoc Biol. 2016 Jun 27.  PMID: 27354410
  23. Al-Saeed AH, Constantino MI, Molyneaux L, D'Souza M, Limacher-Gisler F, Luo C, Wu T, Twigg SM, Yue DK, Wong J. An Inverse Relationship Between Age of Type 2 Diabetes Onset and Complication Risk and Mortality: The Impact of Youth-Onset Type 2 Diabetes.
    Diabetes Care. 2016;39 (5):823-9. PMID: 27006511
  24. McGill M, Felton AM for the Global Partnership. Treatment urgency: the importance of getting people with type 2 diabetes to target promptly. Diabetes Research and Clinical Practice 2016; 117:100-103
  25. Kexin Eh, Margaret McGill, Jencia Wong, Ines Krass, Cultural issues and other factors that affect self-management of Type 2 Diabetes Mellitus (T2D) by Chinese immigrants in Australia.  Diabetes Research and Clinical Practice 1 1 9 ( 2 0 1 6 ) 9 7 -1 0 5
  26. Williams KH, Sullivan DR, Veillard AS, O'Brien R, George J, Jenkins AJ, Young S, Ehnholm C, Duffield A, Twigg SM, Keech AC. Low alanine aminotransferase levels and higher number of cardiovascular events in people with Type 2 diabetes: analysis of the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. Diabet Med. 2016;33(3):356-64.
  27. Williams KH, Sullivan DR, Nicholson GC, George J, Jenkins AJ, Januszewski AS, Gebski VJ, Manning P, Tan YM, Donoghoe MW, Ehnholm C, Young S, O'Brien R, Buizen L, Twigg SM, Keech AC. Opposite associations between alanine aminotransferase and γ-glutamyl transferase levels and all-cause mortality in type 2 diabetes: Analysis of the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. Metabolism. 2016;65(5):783-93.
  28. Yeap BB, Knuiman MW, Divitini ML, Hui J, Arscott GM, Handelsman DJ, McLennan SV, Twigg SM, McQuillan B, Hung J, Beilby JP. Epidemiological and Mendelian Randomization Studies of Dihydrotestosterone and Estradiol and Leukocyte Telomere Length in Men. J Clin Endocrinol Metab. 2016;101(3):1299-306.
  29. Lanting SM, Twigg SM, Johnson NA, Baker MK, Caterson ID, Chuter VH.
    Non-invasive lower limb small arterial measures co-segregate strongly with foot complications in people with diabetes. J Diabetes Complications. 2016. S1056-8727(16)30488-3.
  30. Insulin-like growth factor binding protein-3 links obesity and breast cancer progression. Scully T, Firth SM, Scott CD, de Silva HC, Pintar JE, Chan-Ling T, Twigg SM, Baxter RC. Oncotarget. 2016;7(34):55491-55505.
  31. Sweeting A, Caterson I. Approaches to obesity management. Internal Medicine Journal 2017; 47: 734–746
  32. Sweeting A, Appelblom H, Ross GP, Wong J, Kouru H, Williams P, Sairanen M, Hyett JA. A first trimester prediction model for gestational diabetes utilizing aneuploidy and pre-eclampsia screening markers. The Journal of Maternal-Fetal & Neonatal Medicine. Published online 18 June 2017
  33. Sweeting A, Ross GP, Hyett JA, Wong J. Comment: An update on Gestational Diabetes Mellitus in the first trimester: Is early testing justified? Lancet Diabetes & Endocrinology. Published online 28 February 2017
  34. Sweeting A, Appelblom H, Ross GP, Wong J, Kouru H, Williams P, Sairanen M, Hyett JA. First Trimester Prediction of Gestational Diabetes Mellitus: A Clinical Model Based on Maternal Demographic Parameters. Diabetes Research & Clinical Practice 2017; 127:44-50.
  35. Sweeting AN, Wong J, Appelblom H, Ross GP, Kouru H, Williams PF, Sairanen M, Hyett JA. A first trimester prediction model for gestational
    diabetes utilizing aneuploidy and pre-eclampsia screening markers. J. Matern Fetal Neonatal Med. 2017; 18 (6):1-9
  36. Sweeting AN, Ross GP, Hyett J, Wong J. Gestational diabetes in the first trimester: is early testing justified? The Lancet Diabetes & Endocrinology, 2017; 5(8):578-579
    Ross GP. Optimising pregnancy outcomes for women with pre-gestational diabetes in primary health care. Diabetes & Primary Care Australia 2017; 2: 54–9
  37. Morrison M, Audehm R, Barry A, Hendrieckx C, Nankervis A, Porter C, Scibilia R, Ross GP. Resources to support preconception care for women with diabetes, Diabetes & Primary Care Australia 2017; 2: 1-5
  38. Kizirian NV, Goletzke J, Brodie S, Atkinson FS, Markovic TP, Ross GP, Buyken A, Brand-Miller JP. Lower glycemic load meals reduce diurnal glycemic oscillations in women with risk factors for gestational diabetes. BMJ Open Diabetes Res Care. 2017; 5(1):e000351
  39. Sweeting AN, Ross GP, Hyett J, Molyneaux L, Tan K, Constantino M, Harding AJ, Wong J. Baseline HbA1c to Identify High-Risk Gestational Diabetes: Utility in Early vs Standard Gestational Diabetes. J Clin Endocrinol Metab. 2017 102(1):150-156
  40. Wong T, Barnes RA, Ross GP, Cheung NW, Flack JR. Are the Institute of Medicine weight gain targets applicable in women with gestational diabetes mellitus? Diabetologia 2017;60(3):416-423
  41. Constantino MI, Molyneaux L, Wu T, Twigg SM, Wong J, Yue DK: Data collection on retinopathy as a public health tool: The Hubble telescope equivalent of looking back in time. Journal of diabetes and its complications 2017;
  42. Middleton TL, Wong J, Molyneaux L, Brooks BA, Yue DK, Twigg SM, Wu T.  Cardiac Effects of Sulfonylurea-related Hypoglycaemia.  Diabetes Care.  2017; 40(5): 663-670
    Lee AS, Brooks BA, Simmons L, Kilborn MJ, Wong J, Twigg SM & Yue DK. Hypoglycaemia and QT interval prolongation: detection by simultaneous Holter and continuous glucose monitoring. Diabetes Res Clin Pract. 2016; 113: 211-214.
  43. Constantino MI, Al-Saeed AH, Molyneaux L et al.  An inverse Relationship Between Age of Type 2 Diabetes Onset and Complication Risk and Mortality:  The Impact of Youth-Onset Type 2 Diabetes.  Diabetes Care 2016, 9(5): 823-829.
  44. Min D, Brooks B, Wong J, Aamidor S, Seehoo R, Sutanto S, Harrisberg B, Yue DK, Twigg SM, McLennan SV Monocyte CD163 is altered in association with diabetic complications: possible protective role. J Leukoc Biol. 2016 Jun 27.  PMID: 27354410
  45. Al-Saeed AH, Constantino MI, Molyneaux L, D'Souza M, Limacher-Gisler F, Luo C, Wu T, Twigg SM, Yue DK, Wong J. An Inverse Relationship Between Age of Type 2 Diabetes Onset and Complication Risk and Mortality: The Impact of Youth-Onset Type 2 Diabetes.
    Diabetes Care. 2016;39 (5):823-9. PMID: 27006511
  46. McGill M, Felton AM for the Global Partnership. Treatment urgency: the importance of getting people with type 2 diabetes to target promptly. Diabetes Research and Clinical Practice 2016; 117:100-103
  47. Kexin Eh, Margaret McGill, Jencia Wong, Ines Krass, Cultural issues and other factors that affect self-management of Type 2 Diabetes Mellitus (T2D) by Chinese immigrants in Australia.  Diabetes Research and Clinical Practice 1 1 9 ( 2 0 1 6 ) 9 7 –1 0 5
  48. Williams KH, Sullivan DR, Veillard AS, O'Brien R, George J, Jenkins AJ, Young S, Ehnholm C, Duffield A, Twigg SM, Keech AC. Low alanine aminotransferase levels and higher number of cardiovascular events in people with Type 2 diabetes: analysis of the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. Diabet Med. 2016;33(3):356-64.
  49. Andrzej S. Januszewski, Surya S. Sutanto, Susan McLennan, David N. O'Neal, Anthony C Keech, Stephen M. Twigg, Alicia J. Jenkins Shorter telomeres in adults with Type 1 diabetes correlate with diabetes duration, but only weakly with vascular function and risk factors. Diabetes Research and Clinical Practice. 2016;117:4-11.
  50. Williams KH, Sullivan DR, Nicholson GC, George J, Jenkins AJ, Januszewski AS, Gebski VJ, Manning P, Tan YM, Donoghoe MW, Ehnholm C, Young S, O'Brien R, Buizen L, Twigg SM, Keech AC. Opposite associations between alanine aminotransferase and γ-glutamyl transferase levels and all-cause mortality in type 2 diabetes: Analysis of the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. Metabolism. 2016;65(5):783-93.
  51. Yeap BB, Knuiman MW, Divitini ML, Hui J, Arscott GM, Handelsman DJ, McLennan SV, Twigg SM, McQuillan B, Hung J, Beilby JP. Epidemiological and Mendelian Randomization Studies of Dihydrotestosterone and Estradiol and Leukocyte Telomere Length in Men. J Clin Endocrinol Metab. 2016;101(3):1299-306.
  52. Non-invasive lower limb small arterial measures co-segregate strongly with foot complications in people with diabetes.Lanting SM, Twigg SM, Johnson NA, Baker MK, Caterson ID, Chuter VH.
    J Diabetes Complications. 2016. S1056-8727(16)30488-3.
  53. Insulin-like growth factor binding protein-3 links obesity and breast cancer progression. Scully T, Firth SM, Scott CD, de Silva HC, Pintar JE, Chan-Ling T, Twigg SM, Baxter RC. Oncotarget. 2016;7(34):55491-55505. Premixed insulin analogues: A new look at an established option
    Wu T (2016) Premixed insulin analogues: A new look at an established option. Diabetes & Primary Care Australia 1 (4): 129–33

Book Chapters:
  1. Sweeting A, Caterson ID. Control of Weight: How Do We Get Fat? In: Textbook of Diabetes. Ed. R. I. G. Holt, C. S. Cockram, A. Flyvbjerg & B. J. Goldstein. John Wiley & Sons, Ltd, Chichester, UK. Chapter 9.

Presentations:
  1. Brooks B, Middleton T, Constantino M, Wu T, Yue DK, Wong J. Parental history and age of onset of type 2 diabetes: the role of paternal factors in young onset type 2 diabetes (YT2D). American Diabetes Association, 76th Annual Scientific Meeting 2016
  2. Brooks B, Middleton T, Constantino M, Wu T, Yue DK, Wong J. The role of paternal factors in young onset type 2 diabetes (YT2DM). Australian Diabetes Society ASM, Gold Coast 2016
  3. Brooks B. Type 2 diabetes in young people: are we paying them enough attention? Wuhan Hospital, China 2017 (symposium speaker)
  4. Cardiac Effects of Sulfonylurea-related Hypoglycemia: increased QT dynamicity and ectopy. American Diabetes Association, 76th Annual Scientific Sessions 2016
  5. Clarkson S, Constantino M, Overland J, McGill M, Wu T, Ross G, Twigg S, Wong J. The high frequency and frequent variations of inpatient hyper- and hypoglycaemia in a large teaching hospital. Australian Diabetes Educators Association ASM, Gold Coast 2016
    Diabetes and Driving.
  6. Twigg SM. Invited Talk, Australian Diabetes Society ASM, Gold Coast 2016
  7. Franklin JL, Franklin R, Manson E, Picone TJ, Loughnan G, Markovic TP. How Do People With Obesity Perceive Injury?, 13th International Congress on Obesity. Vancouver Canada, May 2016.
  8. Franklin JL, Manson E, Picone TJ, Loughnan G, Markovic TP. Are Importance Of Weight Loss And Confidence In One's Ability To Achieve Weight Loss Meaningful Measures?13th International Congress on Obesity taking place in Vancouver Canada, May 2016.
  9. Griffiths C , Brooks B, Landy E, Shi Y, Gauld A, Constantino M, Middleton T, Wu T, Yue DK, Wong J.  Young onset type 2 diabetes: Out of Touch and Out of Time. Australian Diabetes Society ASM, Gold Coast 2016
  10. Griffiths C, Brooks B, Landy E, Shi Y, Gauld A, Middleton T, Constantino M, Yue DK. Poor Clinic Attendance of Young Onset Type 2 Diabetes: Out of Touch and Out of Time. American Diabetes Association, 77th Annual Scientific Meeting 2017.
  11. Griffiths C, Overland J, Sainsbury A, Little T, Franklin J, Gibson A, Toth K, Gauld A, Wong J. Intermittent Fasting: appears an effective and safe strategy for weight less and metabolic control in Type 2 Diabetes. Australian Diabetes Society ASM, Gold Coast 2016
  12. Gu Y,  Lee M, Dennis S, Wong J, Gauld A, Munoz P, Harmer A. Peripheral Nerve Excitability Profile in People with Early-Onset Type 2 Diabetes mellitus Without Clinical Symptoms of Neuropathy. Australian Physiotherapy Association APA Sydney 2017
  13. Hetherington J. Endocrine Disruption Aftermath with Newer Oncology Agents. Novartis Nurses Workshop Endocrine Nurses Society of Australasia/ Oncology Nurses Australia, October 2016.
  14. Hetherington J. The Insulin Tolerance Test - A New Angle On An Old Problem - Endocrine Nurses Society Annual Symposium/Endocrine Society Meeting Boston, April 2016.
  15. Hetherington J. The Insulin Tolerance Test - A New Angle on How to Improve Safety.  Federation of International Nurses in Endocrinology Symposium Program/International Congress of Endocrinology Beijing,  September 2016.
  16. Hsieh A., Williams PF. Shades of Graves: a holistic coverage of Graves' Disease from the patient, clinician and laboratory perspective.  AACB AIMS Combined Scientific Meeting Industry Symposia, September 2016.
  17. J. Overland, K Toth, A Sainsbury, T Little, J Franklin, A Gibson, A Gauld, J Wong. The 5:2 STOP Study: A pilot study to compare the metabolic effects and safety of weight loss via intermittent fasting versus standard continuous energy restriction in patients with Type 1 diabetes and overweight or obesity. Australian Diabetes Society ASM, Gold Coast 2016
  18. Landy E, Griffiths C, Brooks B, Shi Y, Gauld A, Constantino M,  Middleton T, Salgo A, Wu T, Yue DK, Wong J. Are We Too Reassuring To Our Patients With Young Onset Type 2 Diabetes? Australian Diabetes Educators Association ASM, Gold Coast 2016
  19. Lee AS, Twigg SM, Flack JR.  Metformin usage in adults with type 1 diabetes in the Australian National Diabetes Information Audit and Benchmarking (ANDIAB) Initiative. Poster presentation at the Annual Scientific Meeting of the Australian Diabetes Society 2016, Gold Coast.
  20. Loughnan G. A PWS Clinic  - Is It Worth the Effort. 9th International PWS Conference in Toronto, Canada, 2016.
  21. M. McGill Invited speaker Diabetes in Australia. International Diabetes Federation Western Pacific Region, Taipei, Taiwan
  22. M. McGill Invited speaker How to provide the best diabetes education. International Diabetes Federation Western Pacific Region, Taipei, Taiwan
  23. Margaret McGill, Vincent Wong, Lynda Molyneaux, Maria Constantino, Ted Wu, Dennis Yue, Jencia Wong. A Poll to determine ethnic differences of diabetes in Australia. Australian Diabetes Society ASM, Gold Coast 2016
  24. Markovic TP. Bariatric Surgery in Australia: private vs public sector. International Congress on Obesity and Metabolic Syndrome, Seoul, Korea, 2016.
  25. McGill M. Diabetes and the Elderly.  The Shijiazhuang Second Hospital, Hebei Province China 2016
  26. McGill M. Invited speaker Diabetes in Australia. International Diabetes Federation Western Pacific Region, Taipei, Taiwan
  27. McGill M. Invited speaker How to provide the best diabetes education. International Diabetes Federation Western Pacific Region, Taipei, Taiwan
  28. Middleton T, Molyneaux L, Brooks B, Yue D, Twigg S, Wong J, Wu T.
  29. Middleton T, Molyneaux L, Brooks B, Yue D, Twigg S, Wong J, Wu T. Cardiac Effects of Sulfonylurea-related Hypoglycemia: increased QT dynamicity and ectopy. American Diabetes Association, 76th Annual Scientific Sessions 2016
  30. Middleton T, Molyneaux L, Brooks B, Yue DK, Twigg SM, Wong J, Wu T. Sulfonylurea therapy, hypoglycaemia, glycaemic variability and changes in ventricular repolarisation. Australian Diabetes Society ASM, Gold Coast 2016
  31. Middleton TL, Constantino MI, Molyneaux L, Twigg SM, Wu T, Wong J.  Microvascular Complications in Young Adult Onset Type 2 Diabetes: Independent Associations with Increased Retinopathy, American Diabetes Association, 77th Annual Scientific Meeting 2017 (Moderated Poster Presentation)
  32. Mijatovic J, Capling L, Cheng S, Louie J, Cheung N, Markovic T, Stamatakis E, Ross G, Brand-Miller J, Flood V. A systematic literature review exploring dietary intake & levels of physical activity as predictors of gestational diabetes mellitus. American Diabetes Association 77th Scientific Sessions San Diego 2017.
  33. Overland J, Griffiths C, Gauld A, Gibson A, Franklin J, Toth A, Sainsbury A, Wong J. Intermittent Fasting versus Continuous Energy Restriction: A pilot study in people with Type 2 diabetes and overweight and obesity. Poster presented at the American Diabetes Association 77th Scientific Session San Diego. CA. June 2017
  34. Overland J, Toth K, Franklin J, Gibson A, Molyneaux L, Sainsbury A, Wong J. Metabolic Effects and Safety of Weight Loss Via Intermittent Fasting Versus Continuous Energy Restriction in Patients with Type 1 Diabetes And Overweight or Obesity. Presented at the American Diabetes Association 77th Scientific Session San Diego. CA. June 2017
  35. Piotrowicz AK, McGill M, Overland J, Molyneaux L, Twigg SM. An On-line Learning Tool in Type 1 Diabetes That Reduces Exercise-Related Hypoglycemia Including Nocturnal Episodes. American Diabetes Association, 76th Annual Scientific Meeting 2016.
  36. R A Barnes, T Wong, G P Ross, B B Jalaludin, J Wong, M Constantino, L Molyneaux, L MacDonald-Wicks C. Smart, C. Collins and J.R. Flack. Does a validated GDM Insulin Prediction Model work with Different Treatment Targets?  The Australasian Diabetes in Pregnancy Society ASM, Gold Coast, 2016
  37. Sweeting A, Ross G, Hyett J, Molyneaux L, Constantino M, Harding AJ, Wong J. Gestational Diabetes in early pregnancy: Evidence for poor pregnancy outcomes despite treatment. Oral presentation. SLHD Innovations Symposium. Sydney, Australia 22-23rd June 2017.
  38. Tabet EJ, Ross GP, Flack JR. The Diagnosis Of Gestational Diabetes Mellitus After Bariatric Surgery: Are We Off Target? The 9th International Symposium on Diabetes, Hypertension, Metabolic Syndrome and Pregnancy, Barcelona, Spain 2017.
  39. Twigg SM. Invited Speaker Diabetes and Foot Disease, International Diabetes Federation Western Pacific Region, Taipei, Taiwan; Asian Association for the Study of Diabetes Annual Conference. 2016
  40. Twigg SM. Keynote Speaker on Diabetes Complications: 2016 National Diabetes Institute, Kuala Lumpur, Malaysia.
  41. Wong J  Invited Speaker Gestational Diabetes. The Shijiazhuang Second Hospital, Hebei Province China 2016
  42. Wu  T Invited Speaker Latest Diabetes Treatments. The Shijiazhuang Second Hospital, Hebei Province China 2016

Research Grants

GRANTING BODY AWARDEES PROJECT TITLE YEARS total $ Years
NHMRC Project Grant #1127737 Markovic TP Improving weight loss by intermittent use of very low energy diet: the TANGO Diet Trial $660,736 2016-2018
ARC ITTC IC140100026 Deghani F; …;Dong Q, and 22 others ARC Training Centre for the Australian Food Processing Industry in the 21st Century $2,997,000 2014-2016
NSW DoH Translational Research Grant Scheme Nube V; Twigg SM Diabetes Debridement Study $330,000 2016-2018
NHMRC Joint Call Project #1113612 S.M. Twigg,Y. Bi, S. Colagiuri, N. Johnson, SV McLennan  Impact of Exercise Intervention on the Phenome (Metabolism and Predictive Complications) in Well Characterised Prediabetes and New Onset Type 2 Diabetes Cohorts in China and Australia (TheDiabeEx.JointStudy). $567,000 2016-2020
NHMRC Project Grant #1125038 Gorrell MG, McCaughan GW, S.M. Twigg, WW Bachovchin. DPP4 family proteases as drivers of chronic liver injury $730,030 2016-2020

Contact details for department

Head of Department: Prof. Stephen Twigg

Department/Unit: Department of Endocrinology
Address:
Dept of Endocrinology
c/o Charles Perkins Centre, D17, Level 3 West, University of Sydney
Sydney NSW 2006
Telephone: (02) 8627 1890
Facsimile: (02) 8627 1604
Web: https://www.slhd.nsw.gov.au/research/
Email: stephen.twigg@sydney.edu.au