Our Research

Our Research

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Contact Details

  Street address:
Level 11, KGV Building
Missenden Road
CAMPERDOWN NSW 2050
 
Postal address:
Post Office Box M30
Missenden Road NSW 2050

Phone: (02) 9515-6111
Fax: (02) 9515-9610

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Microbiology and Infectious Disease

Our Research

Staff specialists in the department continue to lead an active clinical and laboratory research program.
 

  • Dr Andie Lee has a clinical interest in healthcare-associated infections, and continues her research on optimal interventions to control multi-resistant organisms, in particular methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus.
  • A/Prof Sebastian van Hal has a clinical interest in the genomics of multi-resistant organisms, in particular methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus. In addition, is an active member of the Australian New Zealand Mycology Special Interest Group
  • Dr Rebecca Davis has a clinical interest in infections in immunocompromised patients, particularly solid organ transplant patients and in control and management of infection in neonates.
  • Dr Angie Pinto has a clinical interest in HIV, tropical medicine and antimicrobial resistance and continues her research in antiretroviral drug resistance.

Key Achievements

The Department has ongoing collaborations and a national and international level.
 

  • National collaborations include have been established with links with the Australian Group on Antimicrobial Resistance (AGAR) and Australian and New Zealand Mycoses Interest Group (ANZMIG).
  • International research collaborations in the area of Infection Prevention and Hospital Epidemiology continue with Researchers at the University of Geneva Hospitals in Switzerland as well as the International Society of Chemotherapy (ISC).

Research Staff

  • Dr Andie Lee - Infectious Diseases Physician and Microbiologist at Royal Prince Alfred Hospital, Clinical Senior Lecturer at the University of Sydney and Deputy Registrar at the Royal College of Pathologists of Australasia.
  • A/Prof Sebastian van Hal Infectious Diseases Physician and Microbiologist at Royal Prince Alfred Hospital, Conjoint appointment with University of Western Sydney.
  • Dr Rebecca Davis - Infectious Diseases Physician and Microbiologist at Royal Prince Alfred Hospital, Clinical Senior Lecturer at the University of Sydney.
  • Dr Angie Pinto- Infectious Diseases Physician and Microbiologist at Royal Prince Alfred Hospital

Higher Degree Students:

Masters:

  • Bobby Dimitrijovski: Vancomycin Tolerance


Publications and Presentations

Publication Details:
  1. Lee AS, Huttner B and Harbarth S. Prevention and Control of Methicillin-Resistant Staphylococcus aureus in Acute Care Settings. Infectious Disease Clinics of North America 2016; 30: 931-52
  2. Halliday CL, Chen S, Kidd SE, van Hal S, Chapman B, Heath C, Lee A, Kennedy K, Daveson K, Sorrell T, Morrissey CO, Marriotti DJ, Slavin MA. Antifungal susceptibilities of non-Aspergillus filamentous fungi causing invasive infection in Australia: support for current antifungal guideline recommendations. International Journal of Antimicrobial Agents 2016; 48: 453-8
  3. Menon V, Lahanas S, Janto C, Lee A. Utility of Direct Susceptibility Testing on Blood Cultures - Is It Still Worthwhile? Journal of Medical Microbiology 2016; 65: 501-509
  4. Kennedy K, Daveson K, Slavin M, van Hal S, Sorrell T, Lee A, Marriott D, Chapman B, Halliday C, Hajkowicz K, Athan E, Bak N, Cheong E, Heath C, Morrissey C, Kidd S, Beresford R, Blyth C, Korman T, Robinson J, Chen S. Mucormycosis in Australia: contemporary epidemiology and outcomes. Clinical Microbiology and Infection 2016; 22: 775-781
  5. Menon V, Jo HE, Corte P, Lee AS, Wignall AC, Reddel HK. An unusual cause of laryngotracheobronchitis. Clinical Microbiology Newsletter 2016; 38: 79-86
  6. van Hal SJ, Ip CL, Ansari MA, Wilson DJ, Espedido BA, Jensen SO, Bowden R. Evolutionary dynamics of Enterococcus faecium reveals complex genomic relationships between isolates with independent emergence of vancomycin resistance. Microb Genom. 2016 Jan 19;2(1).
  7. Halliday CL, Chen SC, Kidd SE, van Hal S, Chapman B, Heath CH, Lee A, Kennedy KJ, Daveson K, Sorrell TC, Morrissey CO, Marriott DJ, Slavin MA. Antifungal susceptibilities of non-Aspergillus filamentous fungi causing invasive infection in Australia: support for current antifungal guideline recommendations. Int J Antimicrob Agents. 2016 Oct;48(4):453-8.
  8. McMullan BJ, Bowen A, Blyth CC, Van Hal S, Korman TM, Buttery J, Voss L, Roberts S, Cooper C, Tong SY, Turnidge J. Epidemiology and Mortality of Staphylococcus aureus Bacteremia in Australian and New Zealand Children. JAMA Pediatr. 2016 Oct 1;170(10):979-986.
  9. Tong SY, Nelson J, Paterson DL, Fowler VG Jr, Howden BP, Cheng AC, Chatfield M, Lipman J, Van Hal S, O'Sullivan M, Robinson JO, Yahav D, Lye D, Davis JS; CAMERA2 study group and the Australasian Society for Infectious Diseases Clinical Research Network. CAMERA2 - combination antibiotic therapy for methicillin-resistant Staphylococcus aureus infection: study protocol for a randomised controlled trial.Trials. 2016 Mar 31;17:170.
  10. Kennedy KJ, Daveson K, Slavin MA, van Hal SJ, Sorrell TC, Lee A, Marriott DJ, Chapman B, Halliday CL, Hajkowicz K, Athan E, Bak N, Cheong E, Heath CH, Morrissey CO, Kidd S, Beresford R, Blyth C, Korman TM, Robinson JO, Meyer W, Chen SC; Australia and New Zealand Mycoses Interest Group of the Australasian Society for Infectious Diseases. Mucormycosis in Australia: contemporary epidemiology and outcomes. Clin Microbiol Infect. 2016 Sep;22(9):775-781.
  11. Fletcher S, Sibbritt D, Stark D, Harkness J, Rawlinson W, Andresen D, Van Hal S, Merif J, Ellis J. Descriptive epidemiology of infectious gastrointestinal illnesses in Sydney, Australia, 2007-2010.Western Pac Surveill Response J. 2015 Oct 6;6(4):7-16.
  12. Kullar R, Sakoulas G, Deresinski S, van Hal SJ. When sepsis persists: a review of MRSA bacteraemia salvage therapy. J Antimicrob Chemother. 2016 Mar;71(3):576-86.
  13. Davis JS, Sud A, O'Sullivan MV, Robinson JO, Ferguson PE, Foo H, van Hal SJ, Ralph AP, Howden BP, Binks PM, Kirby A, Tong SY; Combination Antibiotics for MEthicillin Resistant Staphylococcus aureus (CAMERA) study group.; Australasian Society for Infectious Diseases Clinical Research Network. Combination of Vancomycin and β-Lactam Therapy for Methicillin-Resistant Staphylococcus aureus Bacteremia: A Pilot Multicenter Randomized Controlled Trial. Clin Infect Dis. 2016 Jan 15;62(2):173-80.
  14. Pudipeddi AV, Liu K, Watson GF, Davis RJ, Strasser SI. Cryptococcal osteomyelitis of the skull in a liver transplant patient. Transpl Infect Dis. 2016 Dec;18(6):954-956.
  15. Sasson SC, Davies S, Chan R, Davies L, Garcia R Cerebral toxoplasmosis in a patient with myasthenia gravis and thymoma with immunodeficiency/Good's syndrome: a case report BMC Infectious Diseases 2016; 16:457

Book Chapters:
  1. Pinto AN, Cooper DA. Tenofovir. In: Kucers' The Use of Antibiotics, Seventh Edition: A Clinical Review of Antibacterial, Antifungal, Antiparasitic and Antiviral Drugs. CRC Press | Taylor & Francis Group (in press)

Presentations:
  1. Andie Lee (Invited Speaker) - Prosthetic joint infections. Update in Major Revision Arthroplasty and Limb Salvage, Sanctuary Cove Qld 2016 (National Conference)
  2. A/Prof van Hal (Invited Speaker) ID Forum 2016: An update on vancomycin-resistant Enterococcal infections: Resistance, therapeutic considerations and when to treat (National Conference -Sydney)
  3. A/Prof van Hal MMM 2016: Vancomycin Resistance what have we learnt. (National Conference- Canberra)
  4. Angie Pinto ASID 2016: Changing Mortality and Cause of Death in an Australian Cohort of Primary HIV Infection (National Conference- Launceston)
  5. Angie Pinto ASHM 2016: Prevalence of Integrase Strand Transfer Inhibitor Genotypic Resistance in Clinical Specimens in NSW, 2012-2015 (National Conference- Adelaide)
  6. Chan RC [invited speaker] Quality and Accreditation Pathology Management Course 2016 Royal College of Pathologists of Australasia, October 2016, Sydney (National meeting)

Research Grants

GRANTING BODY AWARDEES PROJECT TITLE Total $$ Years
NHMRC Dr Joshua Davis - CIE at RPA Sebatian Vanhal CAMERA: Combination antibiotic treatment for Methicillin Resistant Staphylococcus Aureus Bacteraemia - a Randomised Controlled Trial  $ 1,113,531 2015-2019

Contact details for department

Head of Department: Dr Raymond Chan

Department/Unit: Microbiology and Infectious Disease
Address:
Department of Microbiology, Level 6 Building 65,
RPA Hospital, Missenden Road
Camperdown NSW 2050
Telephone: (02) 9515 5026
Facsimile: (02) 9515 5235
Web: www.slhd.nsw.gov.au/research/
Email: raymond.chan@health.nsw.gov.au