Royal Prince Alfred Hospital
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Contact Details

  Street address:
Level 11, KGV Building
Missenden Road
Postal address:
Post Office Box M30
Missenden Road NSW 2050

Phone: (02) 9515-6111
Fax: (02) 9515-9610

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About RPA

Royal Prince Alfred Hospital is one of Australia's premier tertiary referral hospitals and is recognised as a worldwide leader in healthcare excellence and innovation. RPA is part of a network of hospitals within the Sydney Local Health District. It is the principal teaching hospital of the University of Sydney.

Since its foundation in 1882, RPA has been a respected provider of healthcare, maintaining the philosophy that our doors are always open to those who need our help.

RPA became a household name when the top rating television series the RPA Show took the stories of our patients into the lounge rooms of thousands of families around Australia and overseas.

RPA provides an extensive range of diagnostic and treatment services to more people in NSW than any other public hospital. More than 1000 patients are treated at RPA every day.

History of RPA

Royal Prince Alfred Hospital (RPA) was named after Queen Victoria's second son, His Royal Highness Prince Alfred, later Duke of Edinburgh. During a visit to Australia in 1868 Prince Alfred was the victim of an assassination attempt while on a picnic in the northern Sydney suburb of Clontarf.

Australians opened a public subscription fund to build a hospital as a memorial to his safe recovery. The prince authorised his coat of arms to be used as the new hospital's crest. King Edward VII granted the hospital its Royal prefix in 1902.

More than 125 years of Service

RPA opened as a 146-bed hospital and received its first patients in 1882 at the Missenden Road site. During that year 1069 patients were admitted.

Now widely acknowledged for its tradition of medical innovation and leadership, RPA is responsible for producing many of the country's top clinicians. Its national and international reputation for excellence has long been established through the efforts of staff in patient care, teaching, research and support services, making it one of the State's premier tertiary referral hospitals.

Pioneers in Patient Care

RPA medical and nursing staff have made some outstanding contributions to healthcare during its 135-year history, including these Australian-firsts:

  • First liver transplant
  • First aortic valve replacement
  • First nuclear medicine department
  • First use of triage nurses
  • First Perinatal Medicine Unit and first foetal heart monitor
  • First major Haemophilia Centre
  • First academic dermatology service
  • First Gynaecological Oncology unit in Australia
  • First psychiatric assessment unit for deaf and hearing impaired
  • First sleep disorders centre in Australia
  • First National Medical Cyclotron and Positron Emission Tomography Camera

RPA has a proud tradition of leading healthcare innovation and research in NSW, including:

  • The first open heart surgery in NSW
  • The first and only hospital in NSW to establish a Liver Transplant Unit
  • The first coronary angiography in NSW

Some of the achievements our people have recently achieved include:

  • Establishing of the Southern Hemisphere's only training institute for Robotic Surgery
  • Breakthroughs in gene therapy leading to potentially curative treatments for haemophilia and thalassaemia
  • Using whole genome sequencing to significantly improve the diagnosis rate of hypertrophic cardiomyopathy, a life-threatening heart condition that causes sudden cardiac death
  • Pioneering the technique of extracorporeal irradiation and re-implantation of bone for primary bone sarcoma
  • Designing and building a double humidicrib to help safely deliver twin neonates to other hospitals
  • Discovering of a cell which plays a vital role in preventing harmful microbes from spreading throughout the body by accessing the liver
  • Pioneering a lateral pelvic exenteration surgical approach to the most technically challenging lateral pelvic recurrences within a research framework
  • Setting up NSW's first Neuro-Autonomic Service with highly specialised services in neuro-otology, neuro-immunology and neuromuscular disorders and epilepsy
  • Constructing an off the shelf, ready to use blood vessel for multiple cardiothoracic uses

Excellence in Health

Leading Edge Research

RPA plays an active role in the implementation of innovative medical techniques. Doctors and researchers are continuously trialling new drugs and testing new equipment and procedures.

Ground-breaking research of international interest is regularly published and transferred into patient care at the earliest opportunity. RPA patients are often the first in the country to receive new, more effective forms of treatment.

Innovative Teaching

In 1884, the first 14 medical students were accepted, establishing RPA as the first teaching hospital in NSW. Located adjacent to the medical school of the University of Sydney, RPA has always placed a major emphasis on teaching. It now has the biggest student intake and one of the largest staffs of resident medical officers in NSW.

Numerous structured and accredited training programs are available for doctors wishing to specialise. Doctors and nurses trained at RPA continue to have enormous influence in medical and nursing circles.

To learn more about RPA's history, why not visit its Museum.

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